Chromatic cues for the sign of defocus in the peripheral retina.

IF 2.9 2区 医学 Q2 BIOCHEMICAL RESEARCH METHODS
Len Zheleznyak,Chang Liu,Simon Winter
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引用次数: 0

Abstract

Detecting optical defocus at the retina is crucial for accurate accommodation and emmetropization. However, the optical characteristics of ocular defocus are not fully understood. To bridge this knowledge gap, we simulated polychromatic retinal image quality by considering both the monochromatic wavefront aberrations and chromatic aberrations of the eye, both in the fovea and the periphery (nasal visual field). Our study revealed two main findings: (1) chromatic and monochromatic aberrations interact to provide a signal to the retina (chromatic optical anisotropy) to discern positive from negative defocus and (2) that chromatic optical anisotropy exhibited notable differences among refractive error groups (myopes, emmetropes and hyperopes). These findings could enhance our understanding of the underlying mechanisms of defocus detection and their subsequent implications for myopia control therapies. Further research is needed to explore the retinal architecture's ability to utilize the optical signals identified in this study.
周边视网膜散焦迹象的色度线索。
检测视网膜上的光学散焦对于准确调节和散瞳至关重要。然而,人们对眼球散焦的光学特性还不完全了解。为了弥补这一知识空白,我们模拟了多色视网膜图像质量,同时考虑了眼窝和周边(鼻腔视野)的单色波前像差和色差。我们的研究揭示了两个主要发现:(1) 色差和单色像差相互作用,为视网膜提供了一个信号(色差光学各向异性),以分辨正负离焦;(2) 色差光学各向异性在屈光不正组(近视、散光和远视)中表现出明显的差异。这些发现可以加深我们对离焦检测的基本机制及其对近视控制疗法的影响的理解。我们还需要进一步研究视网膜结构利用本研究发现的光学信号的能力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Biomedical optics express
Biomedical optics express BIOCHEMICAL RESEARCH METHODS-OPTICS
CiteScore
6.80
自引率
11.80%
发文量
633
审稿时长
1 months
期刊介绍: The journal''s scope encompasses fundamental research, technology development, biomedical studies and clinical applications. BOEx focuses on the leading edge topics in the field, including: Tissue optics and spectroscopy Novel microscopies Optical coherence tomography Diffuse and fluorescence tomography Photoacoustic and multimodal imaging Molecular imaging and therapies Nanophotonic biosensing Optical biophysics/photobiology Microfluidic optical devices Vision research.
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