{"title":"Glandular cell products in adult cestode: A new tale of tapeworm interaction with fish innate immune response","authors":"Bahram Sayyaf Dezfuli , Massimo Lorenzoni , Antonella Carosi , Giampaolo Bosi , Emanuela Franchella , Larisa G. Poddubnaya","doi":"10.1016/j.ijppaw.2024.100991","DOIUrl":null,"url":null,"abstract":"<div><p>The caryophyllidean tapeworm <em>Caryophyllaeus brachycollis</em> (Janiszewska, 1953) is indigenous to the Lake Blidinje in the west-central part of Bosnia-Herzegovina where it infects chub <em>Squalius tenellus</em> (Heckel, 1843). Of 22 chubs examined, 45% were infected with <em>C. brachycollis</em> and a total of 912 specimens of this worm were counted. Histopathological and ultrastructural investigations were conducted on interface region between chub intestine and cestode scolex. Different sizes of lipid droplets in cestode tegument, in interface region and in chub enterocytes were observed. <em>C. brachycollis</em> lacks any specialized attachment organs and with an expanded, flattened scolex goes deep in mucosal folds and firmly attaches to them. In the epithelium of fish intestine, near the site of worm attachment, a high number of mucous cells and several rodlet cells were noticed. Indeed, within the intestinal tunica propria-submucosa, beneath the site of scolex attachment, numerous neutrophils and mast cells were encountered. Transmission electron microscopy of the apical part of the scolex of <em>C. brachycollis</em> showed the occurrence of a multicellular, syncytial glandular complex, the scolex produced membrane-bound secretory granules and their fibrillar contents discharged by merocrine and apocrine secretion onto the host-parasite interface. Our results are among the first to provide evidence on the sophisticated relationship between fish intestine and amorphous-undefinable substance produced by scolex glandular complex.</p></div>","PeriodicalId":54278,"journal":{"name":"International Journal for Parasitology-Parasites and Wildlife","volume":"25 ","pages":"Article 100991"},"PeriodicalIF":2.0000,"publicationDate":"2024-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2213224424000877/pdfft?md5=a61d18946052caaa2130931d4e4597fc&pid=1-s2.0-S2213224424000877-main.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal for Parasitology-Parasites and Wildlife","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2213224424000877","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"ECOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
The caryophyllidean tapeworm Caryophyllaeus brachycollis (Janiszewska, 1953) is indigenous to the Lake Blidinje in the west-central part of Bosnia-Herzegovina where it infects chub Squalius tenellus (Heckel, 1843). Of 22 chubs examined, 45% were infected with C. brachycollis and a total of 912 specimens of this worm were counted. Histopathological and ultrastructural investigations were conducted on interface region between chub intestine and cestode scolex. Different sizes of lipid droplets in cestode tegument, in interface region and in chub enterocytes were observed. C. brachycollis lacks any specialized attachment organs and with an expanded, flattened scolex goes deep in mucosal folds and firmly attaches to them. In the epithelium of fish intestine, near the site of worm attachment, a high number of mucous cells and several rodlet cells were noticed. Indeed, within the intestinal tunica propria-submucosa, beneath the site of scolex attachment, numerous neutrophils and mast cells were encountered. Transmission electron microscopy of the apical part of the scolex of C. brachycollis showed the occurrence of a multicellular, syncytial glandular complex, the scolex produced membrane-bound secretory granules and their fibrillar contents discharged by merocrine and apocrine secretion onto the host-parasite interface. Our results are among the first to provide evidence on the sophisticated relationship between fish intestine and amorphous-undefinable substance produced by scolex glandular complex.
期刊介绍：
The International Journal for Parasitology: Parasites and Wildlife (IJP-PAW) publishes the results of original research on parasites of all wildlife, invertebrate and vertebrate. This includes free-ranging, wild populations, as well as captive wildlife, semi-domesticated species (e.g. reindeer) and farmed populations of recently domesticated or wild-captured species (e.g. cultured fishes). Articles on all aspects of wildlife parasitology are welcomed including taxonomy, biodiversity and distribution, ecology and epidemiology, population biology and host-parasite relationships. The impact of parasites on the health and conservation of wildlife is seen as an important area covered by the journal especially the potential role of environmental factors, for example climate. Also important to the journal is ''one health'' and the nature of interactions between wildlife, people and domestic animals, including disease emergence and zoonoses.
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