{"title":"Antimicrobial resistance (AMR) in Orthopaedic surgeries: A Complex issue and global threat","authors":"Amit Lakhani , Karan Jindal , Kavin Khatri","doi":"10.1016/j.jorep.2024.100466","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction</h3><p>Antimicrobial resistance (AMR) in orthopedic surgeries presents significant challenges in terms of prevention, management, and outcomes. Orthopedic procedures, especially those involving implants, are highly susceptible to infections, which can be catastrophic when caused by resistant organisms.</p></div><div><h3>Causes</h3><p>Antimicrobial resistance (AMR) in orthopedic surgeries is driven by several causes and contributing factors. These include prolonged hospital stay and increased use of implants (which can serve as surfaces for biofilm formation by resistant bacteria). Inadequate sterilization of surgical instruments and poor infection control practices further exacerbate the risk of introducing resistant organisms.</p></div><div><h3>Conclusions</h3><p>Addressing AMR in orthopedics necessitates a multifaceted approach, including stringent antibiotic stewardship programs, robust infection control practices, and ongoing research into new antimicrobial agents and alternative treatments. This article provides detailed insights into AMR in the context of orthopedic surgeries. Implementing stricter antibiotic stewardship programs that emphasize appropriate prescribing based on culture and sensitivity testing is crucial.</p></div>","PeriodicalId":100818,"journal":{"name":"Journal of Orthopaedic Reports","volume":"4 4","pages":"Article 100466"},"PeriodicalIF":0.0000,"publicationDate":"2024-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773157X24001619/pdfft?md5=8eb74b039874eccacc24d30885612db6&pid=1-s2.0-S2773157X24001619-main.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Orthopaedic Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2773157X24001619","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Introduction
Antimicrobial resistance (AMR) in orthopedic surgeries presents significant challenges in terms of prevention, management, and outcomes. Orthopedic procedures, especially those involving implants, are highly susceptible to infections, which can be catastrophic when caused by resistant organisms.
Causes
Antimicrobial resistance (AMR) in orthopedic surgeries is driven by several causes and contributing factors. These include prolonged hospital stay and increased use of implants (which can serve as surfaces for biofilm formation by resistant bacteria). Inadequate sterilization of surgical instruments and poor infection control practices further exacerbate the risk of introducing resistant organisms.
Conclusions
Addressing AMR in orthopedics necessitates a multifaceted approach, including stringent antibiotic stewardship programs, robust infection control practices, and ongoing research into new antimicrobial agents and alternative treatments. This article provides detailed insights into AMR in the context of orthopedic surgeries. Implementing stricter antibiotic stewardship programs that emphasize appropriate prescribing based on culture and sensitivity testing is crucial.
导言骨科手术中的抗菌药耐药性(AMR)给预防、管理和治疗效果带来了巨大挑战。骨科手术,尤其是涉及植入物的手术,极易发生感染,如果感染是由耐药生物引起的,则可能造成灾难性后果。这些因素包括住院时间延长和植入物使用增加(植入物可作为耐药细菌形成生物膜的表面)。结论解决骨科的 AMR 问题需要采取多方面的措施,包括严格的抗生素管理计划、健全的感染控制措施以及对新型抗菌药物和替代治疗方法的持续研究。本文将详细介绍骨科手术中的 AMR。实施更严格的抗生素管理计划,强调根据培养和药敏试验开具适当的处方至关重要。