Utilization of microdroplet as optical lens for Surface-Enhanced Raman Spectrometry (SERS) enhancement on localized silver nanoparticle-decorated porous silicon substrate

IF 6.1 2区工程技术 Q1 BIOCHEMICAL RESEARCH METHODS

Lab on a Chip Pub Date : 2024-09-18 DOI:10.1039/d4lc00550c

Chia-Wen Tsao, Zi-Yi Yang

引用次数: 0

Abstract

Surface-Enhanced Raman Spectroscopy (SERS) is a widely used analytical technique known for its high sensitivity and broad applicability. Despite its potential, SERS faces challenges related to detection sensitivity and reproducibility. This study proposes an innovative method to enhance SERS performance by employing water microdroplets as optical lenses on localized silver nanoparticle-decorated porous silicon (LocAg-PS) substrates. The hydrophobic nature of the LocAg-PS substrate not only ensures precise positioning of the microdroplet lenses on the silver nanoparticles grafted pad (AgNPs pad), but also form a plano-convex-like microdroplet lens for the focusing of the excitation laser and the collection of scattered light. Experimental results demonstrate that the use of microdroplet lenses enhances the SERS signal intensity and reproducibility, providing a rapid and cost-effective solution for advanced SERS analysis.

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利用微液滴作为光学透镜，在局部银纳米粒子装饰的多孔硅基底上增强表面增强拉曼光谱（SERS）

表面增强拉曼光谱（SERS）是一种广泛使用的分析技术，以其高灵敏度和广泛的适用性而著称。尽管潜力巨大，但 SERS 在检测灵敏度和可重复性方面仍面临挑战。本研究提出了一种创新方法，通过在局部银纳米颗粒装饰的多孔硅（LocAg-PS）基底上使用水微滴作为光学透镜来提高 SERS 性能。LocAg-PS 基质的疏水性不仅确保了微滴透镜在银纳米粒子接枝垫（AgNPs 垫）上的精确定位，而且还形成了一个平面凸透镜状的微滴透镜，用于聚焦激发激光和收集散射光。实验结果表明，微滴透镜的使用增强了 SERS 信号强度和可重复性，为先进的 SERS 分析提供了一种快速、经济的解决方案。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Lab on a Chip 工程技术-化学综合

CiteScore

11.10

自引率

8.20%

发文量

434

审稿时长

2.6 months

期刊介绍： Lab on a Chip is the premiere journal that publishes cutting-edge research in the field of miniaturization. By their very nature, microfluidic/nanofluidic/miniaturized systems are at the intersection of disciplines, spanning fundamental research to high-end application, which is reflected by the broad readership of the journal. Lab on a Chip publishes two types of papers on original research: full-length research papers and communications. Papers should demonstrate innovations, which can come from technical advancements or applications addressing pressing needs in globally important areas. The journal also publishes Comments, Reviews, and Perspectives.