Estimated cardiorespiratory fitness level and utilization of antidepressants among older adults before and after the COVID-19 lockdown: Findings from the HUNT4 Trondheim 70+ study

IF 2.3 3区医学 Q2 PSYCHIATRY

Mental Health and Physical Activity Pub Date : 2024-09-12 DOI:10.1016/j.mhpa.2024.100631

Maren Lerfald , Linn Marita Hagen , Ekaterina Zotcheva , Federico Palumbo , Audun Havnen , Linda Ernstsen

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引用次数: 0

Abstract

Background

Cardiorespiratory fitness (CRF) refers to the capacity of the cardiovascular and respiratory system to process oxygen. CRF is associated with depressive symptoms and findings suggest that CRF decreased significantly in older adults during the COVID-19 pandemic. However, purchase of prescribed antidepressants before and after the pandemic lockdown by CRF level in older adults has not yet been described.

Methods

This longitudinal study included 1221 community-dwelling older adults ≥70 years old participating in the Norwegian HUNT4 Trondheim 70+ study (2018–2019). Data on estimated CRF (eCRF) were linked to the Norwegian Prescribed Drug Registry and utilized defined daily doses (DDDs) of antidepressants from January 2019 throughout December 2021. Paired t-tests were performed to assess changes in DDDs before and after the Norwegian COVID-19 lockdown in March 2020.

Results

Participants had a mean (M) and standard deviation (SD) age of 76.5 (5.2) years, 53.6% were women. In the total sample, the results showed a significant rise in purchase of antidepressants from before (M = 1.25, SD = 7.17) compared to after the lockdown (M = 1.52, SD = 7.86); t (1220) = −2.47, p = 0.014). The number of participants purchasing antidepressants also increased in the total sample and within each of the eCRF groups. In the different eCRF groups, only individuals in the highest eCRF tertile showed a significant higher purchase of antidepressants after the lockdown (M = 1.44, SD = 6.65); t (413) = −2.63, p = 0.009) compared to the year before (M = 0.99, SD = 5.21).

Conclusions

Compared to before the COVID-19 pandemic lockdown, the utilization of antidepressants increased in community-dwelling older adults, with the steepest increase observed among those with the highest eCRF levels.

查看原文本刊更多论文

COVID-19 封锁前后老年人的估计心肺功能水平和抗抑郁药物使用情况：HUNT4 特隆赫姆 70 岁以上研究的结果

背景心肺功能（CRF）是指心血管和呼吸系统处理氧气的能力。CRF与抑郁症状有关，研究结果表明，在COVID-19大流行期间，老年人的CRF显著下降。然而，还没有人描述过老年人在大流行封锁前后按CRF水平购买处方抗抑郁药的情况。方法这项纵向研究纳入了参加挪威HUNT4特隆赫姆70岁以上研究（2018-2019年）的1221名社区居住的≥70岁老年人。估算的CRF（eCRF）数据与挪威处方药登记处相关联，并使用了2019年1月至2021年12月期间抗抑郁药物的定义日剂量（DDD）。结果参与者的平均年龄（M）和标准差（SD）为76.5（5.2）岁，53.6%为女性。在所有样本中，结果显示购买抗抑郁药的人数从封锁前（M = 1.25，SD = 7.17）显著上升到封锁后（M = 1.52，SD = 7.86）；t (1220) = -2.47，p = 0.014）。购买抗抑郁药物的参与者人数在总样本和各 eCRF 组别中都有所增加。在不同的 eCRF 组别中，只有最高 eCRF 三元组的参与者在封锁后购买抗抑郁药物的数量（中位数 = 1.44，标准差 = 6.65）显著高于前一年（中位数 = 0.99，标准差 = 5.21）；t (413) = -2.63, p = 0.009。结论与 COVID-19 大流行封锁前相比，居住在社区的老年人对抗抑郁药的使用有所增加，其中 eCRF 水平最高的老年人对抗抑郁药的使用增幅最大。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Mental Health and Physical Activity PSYCHIATRY-

CiteScore

6.70

自引率

6.40%

发文量

审稿时长

32 days

期刊介绍： The aims of Mental Health and Physical Activity will be: (1) to foster the inter-disciplinary development and understanding of the mental health and physical activity field; (2) to develop research designs and methods to advance our understanding; (3) to promote the publication of high quality research on the effects of physical activity (interventions and a single session) on a wide range of dimensions of mental health and psychological well-being (eg, depression, anxiety and stress responses, mood, cognitive functioning and neurological disorders, such as dementia, self-esteem and related constructs, psychological aspects of quality of life among people with physical and mental illness, sleep, addictive disorders, eating disorders), from both efficacy and effectiveness trials;