442 Effects of added 25(OH)D3 with varying standardized total tract digestible phosphorus levels on nursery pig performance, bone and urine characteristics, and serum vitamin D

IF 2.7 2区农林科学 Q1 AGRICULTURE, DAIRY & ANIMAL SCIENCE

Journal of animal science Pub Date : 2024-09-14 DOI:10.1093/jas/skae234.296

Larissa L Becker, Jordan T Gebhardt, Mike D Tokach, Robert D Goodband, Joel M DeRouchey, Jason C Woodworth, Jon R Bergstrom

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引用次数: 0

Abstract

Pigs [n = 360; DNA 600×241; initial body weight (BW) = 5.8 ± 0.54 kg] were used in a 45-d study to evaluate effects of added 25(OH)D3 with three levels of standardized total tract digestible (STTD) P on nursery pig growth performance, bone and urine characteristics, and serum vitamin D status. Pigs were weaned at approximately 19 d of age and randomly allotted to 6 treatments with 5 pigs/pen and 12 replications/treatment. Dietary treatments were arranged in a 2 × 3 factorial with main effects of 25(OH)D3 (0 or 50 µg/kg equivalent to 2,000 IU/kg of vitamin D3; Hy-D, dsm-firmenich, Plainsboro, NJ) and STTD P (70, 100, or 130% of the NRC (2012) requirement on a dietary percentage basis). Diets were corn-soybean meal-based and fed in 3 phases. On d 45, 1 pig/pen was euthanized to collect right fibula, metacarpal, and 2nd and 10th ribs. Overall, increasing STTD P increased (quadratic, P < 0.003) BW, ADG, ADFI, and G/F with minimal improvement above 100% of NRC STTD P requirement. Added 25(OH)D3 had no effect on growth performance (P > 0.10). Pigs fed increasing STTD P had decreased urinary Ca concentration (linear, P < 0.001 and quadratic, P = 0.078) and increased urinary P concentration (quadratic, P < 0.001), with all pigs fed 70% of NRC STTD P requirement having non-detectable levels of urinary P. Added 25(OH)D3 had no effect on urinary Ca and P concentration (P > 0.10). A quadratic 25(OH)D3×STTD P interaction (P = 0.032) was observed for serum 25(OH)D3. When pigs were fed 25(OH)D3, serum 25(OH)D3 increased as STTD P increased (quadratic, P = 0.005) but no differences were observed when no 25(OH)D3 was added and STTD P increased. A quadratic 25(OH)D3×STTD P interaction was observed for serum 1,25(OH)2D3 concentrations (P = 0.002). When pigs were fed 25(OH)D3, serum 1,25(OH)2D3 decreased (quadratic, P < 0.001) as STTD P increased but the decrease was not significant when no 25(OH)D3 was fed. Added 25(OH)D3 had no effect (P > 0.10) on serum 1,25(OH)2D3, but concentrations decreased (quadratic, P = 0.001) as STTD P increased. No added 25(OH)D3×STTD P interaction was observed for 24,25(OH)2D3. Serum 24,25(OH)2D3 increased (P < 0.001) with added 25(OH)D3. Metacarpal bone density increased (linear, P = 0.001) as STTD P increased, as did fibulas and ribs (quadratic, P ≤ 0.055). Percentage bone ash and bone ash weight increased (quadratic, P ≤ 0.065) for all bones as STTD P increased. Added 25(OH)D3 had no effect on bone density or bone ash weight for any bones (P > 0.10); however, the reduction in bone ash observed with reducing STTD P level tended to be less when 25(OH)D3 was provided (linear interaction, P = 0.098). In summary, added 25(OH)D3 had limited effect on growth performance, urine parameters, or bone characteristics; however, added 25(OH)D3 increased serum concentrations of 25(OH)D3 and 24,25(OH)2D3. Increasing STTD P to 100% of NRC requirement estimate increased growth and 130% of NRC maximized bone ash. 5634 Table.pdf

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442 添加 25（OH）D3 和不同的标准化道消化磷水平对育肥猪生产性能、骨骼和尿液特征以及血清维生素 D 的影响

猪[n = 360；DNA 600×241；初始体重 (BW) = 5.8 ± 0.54 kg]被用于一项为期 45 天的研究，以评估添加 25(OH)D3 和三种水平的标准化道消化总量 (STTD) P 对保育猪生长性能、骨骼和尿液特征以及血清维生素 D 状态的影响。猪在大约 19 日龄断奶，随机分配到 6 个处理中，每栏 5 头猪，每个处理 12 个重复。日粮处理以 2 × 3 的阶乘排列，主效应为 25（OH）D3（0 或 50 µg/kg，相当于 2,000 IU/kg 的维生素 D3；Hy-D，dsm-firmenich，Plainsboro，NJ）和 STTD P（按日粮百分比计算，为 NRC（2012）要求的 70%、100% 或 130%）。日粮以玉米-豆粕为基础，分 3 个阶段饲喂。第 45 天，每栏 1 头猪被安乐死，以收集右腓骨、掌骨、第 2 和第 10 根肋骨。总体而言，增加 STTD P 可提高（二次方，P < 0.003）体重、ADG、ADFI 和 G/F，而超过 NRC STTD P 需求量 100% 的改善幅度很小。添加 25(OH)D3 对生长性能没有影响（P & gt; 0.10）。饲喂 STTD P 增加的猪的尿 Ca 浓度降低（线性，P < 0.001 和二次方，P = 0.078），尿 P 浓度增加（二次方，P < 0.001），所有饲喂 NRC STTD P 需求量 70% 的猪的尿 P 水平都检测不到。在血清 25(OH)D3 中观察到 25(OH)D3×STTD P 的二次交互作用（P = 0.032）。给猪饲喂 25（OH）D3 时，血清 25（OH）D3 随 STTD P 的增加而增加（二次方，P = 0.005），但不添加 25（OH）D3 且 STTD P 增加时，没有观察到差异。在血清 1,25(OH)2D3浓度方面，观察到 25(OH)D3×STTD P 的二次交互作用（P = 0.002）。当给猪饲喂 25(OH)D3 时，血清中 1,25(OH)2D3随 STTD P 的增加而降低（二次方，P < 0.001），但当不饲喂 25(OH)D3 时，血清中 1,25(OH)2D3的降低并不显著。添加的 25(OH)D3 对血清 1,25(OH)2D3没有影响（P > 0.10），但随着 STTD P 的增加，血清中的 1,25(OH)2D3浓度降低（二次方，P = 0.001）。对于 24,25(OH)2D3，未观察到添加 25(OH)D3×STTD P 的相互作用。血清 24,25（OH）2D3 随添加 25（OH）D3 而增加（P < 0.001）。掌骨骨密度随着 STTD P 的增加而增加（线性，P = 0.001），腓骨和肋骨也是如此（二次方，P ≤ 0.055）。随着 STTD P 的增加，所有骨骼的骨灰百分比和骨灰重量均增加（二次方，P ≤ 0.065）。添加 25（OH）D3 对任何骨骼的骨密度或骨灰重量都没有影响（P > 0.10）；但是，当提供 25（OH）D3 时，随着 STTD P 水平的降低，观察到的骨灰减少量往往较少（线性交互作用，P = 0.098）。总之，添加 25（OH）D3 对生长性能、尿液参数或骨骼特征的影响有限；但添加 25（OH）D3 可提高血清中 25（OH）D3 和 24,25(OH)2D3 的浓度。将 STTD P 提高到 NRC 需求量估计值的 100%，可提高生长速度，而 NRC 需求量的 130% 则可最大限度地提高骨灰含量。5634 Table.pdf

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来源期刊

Journal of animal science 农林科学-奶制品与动物科学

CiteScore

4.80

自引率

12.10%

发文量

1589

审稿时长

3 months

期刊介绍： The Journal of Animal Science (JAS) is the premier journal for animal science and serves as the leading source of new knowledge and perspective in this area. JAS publishes more than 500 fully reviewed research articles, invited reviews, technical notes, and letters to the editor each year. Articles published in JAS encompass a broad range of research topics in animal production and fundamental aspects of genetics, nutrition, physiology, and preparation and utilization of animal products. Articles typically report research with beef cattle, companion animals, goats, horses, pigs, and sheep; however, studies involving other farm animals, aquatic and wildlife species, and laboratory animal species that address fundamental questions related to livestock and companion animal biology will be considered for publication.