Distribution and risk factors of Trichomonas vaginalis infection with relevance to interleukin profile among population in Duhok city, Iraq

IF 2.3 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
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引用次数: 0

Abstract

Background

Vaginal trichomoniasis is a sexually transmitted disease causes adverse health outcomes, the causative agent is Tichomonas vaginalis. Infected women develop abnormal vaginal discharge with vaginitis. While, men mostly suffer from prostatitis and urethritis.

Objectives

This study aimed to detect the rate of T.vaginalis infection in association with risk factors, measurement of blood parameters, interleukine-2 (IL-2) and interleukine-8(IL-8) levels among individuals.

Methods

A total of 500 females were tested, a vaginal swab and blood were collected from the participants, and they were within the age range of 18–70 years old. High vaginal swabs were examined microscopically using wet mount preparation, the blood used for measurement of blood parameters using coulter count machine and IL-2 and IL-8 levels were evaluated using ELISA technique.

Results

Out of 500 individuals, the prevalence of T. vaginalis infection was 45(9.0 %). The maximum infection rates were reported among age group (18–28) years, rural residents, illiterates, married women (16.7 %), (15.9 %),(30.0 %),(11.7 %),respectively. Moreover, high positivity of infection revealed among low economical level 12.5 % compared to only 1.7 % in high economy group. Unemployed women, those with bad vaginal hygiene showed high incidence of infection 10.5 % and 6.3 %, respectively. It was noted a significant decrease in red blood cells and hemoglobin concentration, however, there was a significantly increased in white blood cells among infected subjects. Furthermore, the levels of both interleukin-2 and interleukin-8 were significantly higher among infected individuals compared to healthy ones.

Conclusions

Effective strategies for disease awareness are needed and should include health promotion, education, and prevention.

伊拉克杜胡克市人口中阴道毛滴虫感染的分布和风险因素与白细胞介素谱的关系
背景阴道滴虫病是一种导致不良健康后果的性传播疾病,病原体是阴道毛滴虫。受感染的女性阴道分泌物异常,并伴有阴道炎。本研究旨在检测滴虫性阴道炎感染率与危险因素的关系,测量血液参数、白细胞介素-2(IL-2)和白细胞介素-8(IL-8)水平。方法共检测了 500 名女性,采集了她们的阴道拭子和血液,她们的年龄在 18-70 岁之间。结果 在 500 人中,阴道拭子感染率为 45(9.0%)。感染率最高的年龄组为(18-28)岁、农村居民、文盲和已婚妇女,分别为(16.7%)、(15.9%)、(30.0%)和(11.7%)。此外,在经济水平较低的人群中,感染阳性率较高,为 12.5%,而在经济水平较高的人群中,感染阳性率仅为 1.7%。失业妇女和阴道卫生不良妇女的感染率分别为 10.5 % 和 6.3 %。感染者的红细胞和血红蛋白浓度明显下降,但白细胞却明显增加。此外,与健康人相比,感染者的白细胞介素-2 和白细胞介素-8 水平均明显升高。
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来源期刊
Clinical Epidemiology and Global Health
Clinical Epidemiology and Global Health PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-
CiteScore
4.60
自引率
7.70%
发文量
218
审稿时长
66 days
期刊介绍: Clinical Epidemiology and Global Health (CEGH) is a multidisciplinary journal and it is published four times (March, June, September, December) a year. The mandate of CEGH is to promote articles on clinical epidemiology with focus on developing countries in the context of global health. We also accept articles from other countries. It publishes original research work across all disciplines of medicine and allied sciences, related to clinical epidemiology and global health. The journal publishes Original articles, Review articles, Evidence Summaries, Letters to the Editor. All articles published in CEGH are peer-reviewed and published online for immediate access and citation.
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