Graphene Metasurfaces-Based Surface Plasmon Resonance Biosensor for Virus Detection with Sensitivity Enhancement Using Perovskite Materials

IF 3.3 4区 物理与天体物理 Q2 CHEMISTRY, PHYSICAL
Jacob Wekalao, Shobhit K. Patel, Fahad Ahmed Al-zahrani
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Abstract

This paper introduces a biosensor based on graphene metasurfaces, designed for virus detection in the terahertz (THz) regime. The proposed sensor comprises four resonators arranged in a semicircular configuration, strategically engineered to achieve enhanced sensitivity and overall performance. Computational simulations using COMSOL Multiphysics version 6.2 were employed to optimize geometric parameters and analyze the sensor’s behavior. By integrating Au, SrTiO₃, graphene, and black phosphorus, the biosensor exhibits remarkable sensitivity to refractive index (RI) variations associated with various viruses. The maximum sensitivity demonstrated by the sensor is 4556 GHzRIU−1. Other remarkable performance metrics include a figure of merit of 8.499 RIU−1, a quality factor of 1.131, and a minimum detection limit of 0.149. Electric field distribution analysis reveals optimal absorption at 0.4 THz. Furthermore, the biosensor demonstrates the potential for 2-bit encoding applications. Compared to existing designs, the proposed biosensor offers significantly higher sensitivity for virus detection. The integration of advanced nanomaterials and metasurface design principles presents a promising avenue for rapid, label-free virus sensing, with potential applications in healthcare and biosecurity.

Abstract Image

基于石墨烯金属表面的表面等离子体共振生物传感器,利用 Perovskite 材料提高病毒检测灵敏度
本文介绍了一种基于石墨烯元表面的生物传感器,设计用于太赫兹(THz)波段的病毒检测。拟议的传感器由四个谐振器组成,呈半圆形配置,经过战略性设计,可实现更高的灵敏度和整体性能。使用 COMSOL Multiphysics 6.2 版进行了计算模拟,以优化几何参数并分析传感器的行为。通过整合金、SrTiO₃、石墨烯和黑磷,该生物传感器对与各种病毒相关的折射率(RI)变化表现出显著的灵敏度。传感器的最大灵敏度为 4556 GHzRIU-1。其他出色的性能指标包括 8.499 RIU-1、1.131 质量因子和 0.149 的最低检测限。电场分布分析表明,在 0.4 太赫兹处有最佳吸收。此外,该生物传感器还展示了 2 位编码应用的潜力。与现有设计相比,所提出的生物传感器具有更高的病毒检测灵敏度。先进纳米材料与元表面设计原理的整合为快速、无标记的病毒传感提供了一条大有可为的途径,在医疗保健和生物安全领域具有潜在的应用前景。
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来源期刊
Plasmonics
Plasmonics 工程技术-材料科学:综合
CiteScore
5.90
自引率
6.70%
发文量
164
审稿时长
2.1 months
期刊介绍: Plasmonics is an international forum for the publication of peer-reviewed leading-edge original articles that both advance and report our knowledge base and practice of the interactions of free-metal electrons, Plasmons. Topics covered include notable advances in the theory, Physics, and applications of surface plasmons in metals, to the rapidly emerging areas of nanotechnology, biophotonics, sensing, biochemistry and medicine. Topics, including the theory, synthesis and optical properties of noble metal nanostructures, patterned surfaces or materials, continuous or grated surfaces, devices, or wires for their multifarious applications are particularly welcome. Typical applications might include but are not limited to, surface enhanced spectroscopic properties, such as Raman scattering or fluorescence, as well developments in techniques such as surface plasmon resonance and near-field scanning optical microscopy.
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