Calculation of the absorbed dose to 99mTc-HMPAO, 99mTc-DMSA, and 99mTc-sulfur colloid injected patients by using Monte Carlo and MIRD methods

IF 1.5 3区化学 Q3 CHEMISTRY, ANALYTICAL

Journal of Radioanalytical and Nuclear Chemistry Pub Date : 2024-09-12 DOI:10.1007/s10967-024-09732-y

Farzane Mohajeri, Ahad Ollah Ezzati

引用次数: 0

Abstract

This study compares the accuracy of dosimetry calculations using the Monte Carlo (MC) method and the MIRD method for ^99mTc-HMPAO, ^99mTc-DMSA, and ^99mTc-sulfur colloid administered to an adult female patient undergoing SPECT imaging. Comparing the two methods, the dose estimation differences between MC and MIRD methods were found to be 11.57%, 1.70%, and 30.04% for ^99mTc-HMPAO, ^99mTc-DMSA, and ^99mTc-sulfur colloid, respectively. In conclusion, this study emphasizes the importance of accurate dosimetry in nuclear medicine. The MC method perform better than the MIRD method in predicting absorbed doses, making it a valuable tool for optimizing radiation therapies and improving patient outcomes.

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使用蒙特卡洛和 MIRD 方法计算注射 99m锝-HMPAO、99m锝-DMSA 和 99m锝-硫胶体患者的吸收剂量

本研究比较了使用蒙特卡洛（Monte Carlo，MC）法和 MIRD 法对接受 SPECT 成像的成年女性患者施用 99m锝-HMPAO、99m锝-DMSA 和 99m锝硫胶体进行剂量测定计算的准确性。比较两种方法，发现 MC 和 MIRD 方法对 99m锝-HMPAO、99m锝-DMSA 和 99m锝- 硫胶体的剂量估计差异分别为 11.57%、1.70% 和 30.04%。总之，这项研究强调了准确剂量测定在核医学中的重要性。MC 方法在预测吸收剂量方面优于 MIRD 方法，是优化放射治疗和改善患者预后的重要工具。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Radioanalytical and Nuclear Chemistry 化学-分析化学

CiteScore

2.80

自引率

18.80%

发文量

504

审稿时长

2.2 months

期刊介绍： An international periodical publishing original papers, letters, review papers and short communications on nuclear chemistry. The subjects covered include: Nuclear chemistry, Radiochemistry, Radiation chemistry, Radiobiological chemistry, Environmental radiochemistry, Production and control of radioisotopes and labelled compounds, Nuclear power plant chemistry, Nuclear fuel chemistry, Radioanalytical chemistry, Radiation detection and measurement, Nuclear instrumentation and automation, etc.