{"title":"Grating Coupled Self-referenced SPP Biosensor for Detection of Glucose Level in Urine in Optical Communication Band","authors":"Lopamudra Sen, Bratati Mukhopadhyay","doi":"10.1007/s11468-024-02494-z","DOIUrl":null,"url":null,"abstract":"<p>The expeditious growth and development of different optical-based medical and biomedical instruments to detect various diseases nowadays put itself a potential research topic. In recent times, prevalence of diabetes mellitus among people has become alarming and often life-threatening. In this regard, efficient sensors with high sensitivity are extremely necessary for monitoring and quantification of glucose level in the urine samples. A self-referenced surface plasmon polariton sensor using trapezoidal TiO<sub>2</sub> grating on thin Au film has been proposed here to detect glucose level in urine samples for the first time. The proposed sensor has been optimized for better sensitivity and can be operated in the optical communication band which can help to achieve existing mature light sources and light detection instruments. The sensor has been designed with a thin dielectric grating on top of thin metal film resulting in generation of two surface plasmons at the two boundaries of the metal film. This technique is fascinating to improve the accuracy of sensitivity of the device and helps to eliminate cross-sensitivity problem. As a result, this type of self-referenced biosensor can be used for a wide range of applications in fields such as biochemistry, biophysics, and environmental monitoring. The proposed sensor shows a higher sensitivity compared to that of other plasmonic sensors reported in recent times due to incorporation of trapezoidal-shaped grating structure for the first time instead of rectangular shape. The spectral sensitivity of the proposed structure was obtained as 666.67 nm/RIU with optimized values of different structural parameters.</p>","PeriodicalId":736,"journal":{"name":"Plasmonics","volume":null,"pages":null},"PeriodicalIF":3.3000,"publicationDate":"2024-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Plasmonics","FirstCategoryId":"101","ListUrlMain":"https://doi.org/10.1007/s11468-024-02494-z","RegionNum":4,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, PHYSICAL","Score":null,"Total":0}
引用次数: 0
Abstract
The expeditious growth and development of different optical-based medical and biomedical instruments to detect various diseases nowadays put itself a potential research topic. In recent times, prevalence of diabetes mellitus among people has become alarming and often life-threatening. In this regard, efficient sensors with high sensitivity are extremely necessary for monitoring and quantification of glucose level in the urine samples. A self-referenced surface plasmon polariton sensor using trapezoidal TiO2 grating on thin Au film has been proposed here to detect glucose level in urine samples for the first time. The proposed sensor has been optimized for better sensitivity and can be operated in the optical communication band which can help to achieve existing mature light sources and light detection instruments. The sensor has been designed with a thin dielectric grating on top of thin metal film resulting in generation of two surface plasmons at the two boundaries of the metal film. This technique is fascinating to improve the accuracy of sensitivity of the device and helps to eliminate cross-sensitivity problem. As a result, this type of self-referenced biosensor can be used for a wide range of applications in fields such as biochemistry, biophysics, and environmental monitoring. The proposed sensor shows a higher sensitivity compared to that of other plasmonic sensors reported in recent times due to incorporation of trapezoidal-shaped grating structure for the first time instead of rectangular shape. The spectral sensitivity of the proposed structure was obtained as 666.67 nm/RIU with optimized values of different structural parameters.
期刊介绍:
Plasmonics is an international forum for the publication of peer-reviewed leading-edge original articles that both advance and report our knowledge base and practice of the interactions of free-metal electrons, Plasmons.
Topics covered include notable advances in the theory, Physics, and applications of surface plasmons in metals, to the rapidly emerging areas of nanotechnology, biophotonics, sensing, biochemistry and medicine. Topics, including the theory, synthesis and optical properties of noble metal nanostructures, patterned surfaces or materials, continuous or grated surfaces, devices, or wires for their multifarious applications are particularly welcome. Typical applications might include but are not limited to, surface enhanced spectroscopic properties, such as Raman scattering or fluorescence, as well developments in techniques such as surface plasmon resonance and near-field scanning optical microscopy.