High-Performance Terahertz Surface Plasmon Resonance Sensor with Graphene-Perovskite Metasurface for Early Cancer Detection

IF 3.3 4区 物理与天体物理 Q2 CHEMISTRY, PHYSICAL
Abdessalem Bouhenna, Oussama Zeggai, Jacob Wekalao, Achouak Achour, Hadj Mouloudj
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Abstract

Cancer continues to be a major global health challenge, where early detection is vital for enhancing patient survival rates. Conventional diagnostic techniques frequently face challenges related to sensitivity and specificity, which can result in delays in obtaining accurate diagnoses. To overcome these obstacles, the creation of highly sensitive and selective biosensors has emerged as a key focus of research. This paper presents the conceptualization and computational simulation of a terahertz surface plasmon resonance (SPR) sensor. The proposed sensor integrates graphene and gold metasurfaces with perovskite material, aimed at cancer detection applications. The sensor architecture is optimized to achieve optimal results. Numerical simulations are conducted to demonstrate the effects of varying graphene chemical potential and resonator dimensions on sensor performance metrics. The optimized configuration demonstrated a maximum sensitivity of 1000 GHzRIU−1 and a figure of merit of 17.241 RIU−1. Analysis of electric field distribution patterns depicts the frequency-dependent electromagnetic wave interactions within the sensor structure. The sensor design also exhibits consistent spectral characteristics, with an FWHM being 0.058 THz and quality factors ranging from 3.328 to 3.517. Furthermore, the proposed sensor demonstrates the promise for encoding applications. The proposed sensor shows considerable promise for early cancer detection applications, potentially contributing to improved diagnostic capabilities and patient outcomes in oncology.

Abstract Image

用于早期癌症检测的石墨烯-超视线金属表面高性能太赫兹表面等离子体共振传感器
癌症仍然是全球健康领域的一大挑战,早期发现对提高患者生存率至关重要。传统诊断技术经常面临灵敏度和特异性方面的挑战,这可能导致无法及时获得准确诊断。为了克服这些障碍,创造高灵敏度和高选择性的生物传感器已成为研究的重点。本文介绍了太赫兹表面等离子体共振(SPR)传感器的概念化和计算模拟。拟议的传感器将石墨烯和金的元表面与过氧化物材料集成在一起,旨在应用于癌症检测。对传感器结构进行了优化,以达到最佳效果。通过数值模拟,证明了不同的石墨烯化学势和谐振器尺寸对传感器性能指标的影响。优化配置的最大灵敏度为 1000 GHzRIU-1,优点系数为 17.241 RIU-1。对电场分布模式的分析描述了传感器结构内与频率相关的电磁波相互作用。传感器设计还表现出一致的光谱特性,FWHM 为 0.058 THz,品质因数为 3.328 至 3.517。此外,拟议的传感器还展示了编码应用的前景。拟议的传感器在早期癌症检测应用方面大有可为,可能有助于提高肿瘤学的诊断能力和病人的治疗效果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Plasmonics
Plasmonics 工程技术-材料科学:综合
CiteScore
5.90
自引率
6.70%
发文量
164
审稿时长
2.1 months
期刊介绍: Plasmonics is an international forum for the publication of peer-reviewed leading-edge original articles that both advance and report our knowledge base and practice of the interactions of free-metal electrons, Plasmons. Topics covered include notable advances in the theory, Physics, and applications of surface plasmons in metals, to the rapidly emerging areas of nanotechnology, biophotonics, sensing, biochemistry and medicine. Topics, including the theory, synthesis and optical properties of noble metal nanostructures, patterned surfaces or materials, continuous or grated surfaces, devices, or wires for their multifarious applications are particularly welcome. Typical applications might include but are not limited to, surface enhanced spectroscopic properties, such as Raman scattering or fluorescence, as well developments in techniques such as surface plasmon resonance and near-field scanning optical microscopy.
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