{"title":"Design of an Efficient Surface Plasmon Resonance Biosensor for Label-Free Detection of Blood Components","authors":"Trupti Kamani, Abdullah Baz, Shobhit K. Patel","doi":"10.1007/s11468-024-02529-5","DOIUrl":null,"url":null,"abstract":"<p>Optical refractive index biosensors are susceptible devices for the assessment of various blood components like blood plasma, WBCs, hemoglobin, RBCs, and diabetes mellitus. These biosensors play a crucial role in various fields, including environmental monitoring, pharmaceuticals, biomedical research, and health care. These devices are designed to detect specific biological molecules or chemical compounds by converting their interactions into measurable signals. This manuscript recommends a detached cyclic refractive index biosensor (DCRIB) for the determination of five respective kinds of blood components. The high-rise sensitivity (S) count of 1400 nm/RIU has been noticed for blood plasma, the high-rise quality factor (QF) count is 769.23 for RBCs, the high-rise figure of merit (FOM) count is 540.43 for RBCs, and the minimum determination limit count is 0.0004895 for diabetes cell, along with a high-rise determination range count of 1225.43 for RBCs.</p>","PeriodicalId":736,"journal":{"name":"Plasmonics","volume":"12 1","pages":""},"PeriodicalIF":3.3000,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Plasmonics","FirstCategoryId":"101","ListUrlMain":"https://doi.org/10.1007/s11468-024-02529-5","RegionNum":4,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, PHYSICAL","Score":null,"Total":0}
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Abstract
Optical refractive index biosensors are susceptible devices for the assessment of various blood components like blood plasma, WBCs, hemoglobin, RBCs, and diabetes mellitus. These biosensors play a crucial role in various fields, including environmental monitoring, pharmaceuticals, biomedical research, and health care. These devices are designed to detect specific biological molecules or chemical compounds by converting their interactions into measurable signals. This manuscript recommends a detached cyclic refractive index biosensor (DCRIB) for the determination of five respective kinds of blood components. The high-rise sensitivity (S) count of 1400 nm/RIU has been noticed for blood plasma, the high-rise quality factor (QF) count is 769.23 for RBCs, the high-rise figure of merit (FOM) count is 540.43 for RBCs, and the minimum determination limit count is 0.0004895 for diabetes cell, along with a high-rise determination range count of 1225.43 for RBCs.
期刊介绍：
Plasmonics is an international forum for the publication of peer-reviewed leading-edge original articles that both advance and report our knowledge base and practice of the interactions of free-metal electrons, Plasmons.
Topics covered include notable advances in the theory, Physics, and applications of surface plasmons in metals, to the rapidly emerging areas of nanotechnology, biophotonics, sensing, biochemistry and medicine. Topics, including the theory, synthesis and optical properties of noble metal nanostructures, patterned surfaces or materials, continuous or grated surfaces, devices, or wires for their multifarious applications are particularly welcome. Typical applications might include but are not limited to, surface enhanced spectroscopic properties, such as Raman scattering or fluorescence, as well developments in techniques such as surface plasmon resonance and near-field scanning optical microscopy.
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