{"title":"Preparation of effective antibacterial composites of low-density polyethylene modified with quaternary ammonium functionalized zinc oxide nanoparticles","authors":"Sipei Zhao, Changlu Zhou, Rui Zan, Mengxuan Shu, Tao Suo, Zhong Xin","doi":"10.1007/s10965-024-04107-z","DOIUrl":null,"url":null,"abstract":"<div><p>The antibacterial activity of biomedical polymer materials is an important basis for their resistance to biofilm contamination as implantable medical devices. However, developing durable and stable antibacterial composites through a universal manufacturing method remains a challenge. Herein, based on an organic–inorganic synergistic antibacterial strategy, functional nanoparticles with high antibacterial performance and better polymer compatibility were prepared by combining zinc oxide nanoparticles (ZnO NPs) with quaternary ammonium compound 3-(trimethoxysilyl)-propyldimethyloctadecyl ammonium chloride (QAS), which containing siloxane group. The ZnO-QAS nanoparticles were then introduced to low-density polyethylene (LDPE) by simple melt blending to manufacture synergistic antibacterial composites. The organic–inorganic hybrid strategy significantly improved the antibacterial activity of the composites, the PE/ZnO-QAS composites possess satisfactory antibacterial efficiency of 99.9% and 99.75% against <i>Escherichia coli</i> (<i>E. coli</i>) and <i>Staphylococcus aureus</i> (<i>S. aureus</i>), respectively, and it could effectively inhibit biofilms. In addition, the functionalization of organic compound QAS provides excellent polymer compatibility for ZnO NPs, which is conducive to their uniform dispersion in LDPE, and comprehensively improves the thermal stability, mechanical properties, and crystallinity of the composites. This provides potential application value for the preparation of long-term stable antibacterial biomedical materials.</p><h3>Graphical Abstract</h3>\n<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":658,"journal":{"name":"Journal of Polymer Research","volume":null,"pages":null},"PeriodicalIF":2.6000,"publicationDate":"2024-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Polymer Research","FirstCategoryId":"92","ListUrlMain":"https://link.springer.com/article/10.1007/s10965-024-04107-z","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"POLYMER SCIENCE","Score":null,"Total":0}
引用次数: 0
Abstract
The antibacterial activity of biomedical polymer materials is an important basis for their resistance to biofilm contamination as implantable medical devices. However, developing durable and stable antibacterial composites through a universal manufacturing method remains a challenge. Herein, based on an organic–inorganic synergistic antibacterial strategy, functional nanoparticles with high antibacterial performance and better polymer compatibility were prepared by combining zinc oxide nanoparticles (ZnO NPs) with quaternary ammonium compound 3-(trimethoxysilyl)-propyldimethyloctadecyl ammonium chloride (QAS), which containing siloxane group. The ZnO-QAS nanoparticles were then introduced to low-density polyethylene (LDPE) by simple melt blending to manufacture synergistic antibacterial composites. The organic–inorganic hybrid strategy significantly improved the antibacterial activity of the composites, the PE/ZnO-QAS composites possess satisfactory antibacterial efficiency of 99.9% and 99.75% against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus), respectively, and it could effectively inhibit biofilms. In addition, the functionalization of organic compound QAS provides excellent polymer compatibility for ZnO NPs, which is conducive to their uniform dispersion in LDPE, and comprehensively improves the thermal stability, mechanical properties, and crystallinity of the composites. This provides potential application value for the preparation of long-term stable antibacterial biomedical materials.
期刊介绍：
Journal of Polymer Research provides a forum for the prompt publication of articles concerning the fundamental and applied research of polymers. Its great feature lies in the diversity of content which it encompasses, drawing together results from all aspects of polymer science and technology.
As polymer research is rapidly growing around the globe, the aim of this journal is to establish itself as a significant information tool not only for the international polymer researchers in academia but also for those working in industry. The scope of the journal covers a wide range of the highly interdisciplinary field of polymer science and technology, including:
polymer synthesis;
polymer reactions;
polymerization kinetics;
polymer physics;
morphology;
structure-property relationships;
polymer analysis and characterization;
physical and mechanical properties;
electrical and optical properties;
polymer processing and rheology;
application of polymers;
supramolecular science of polymers;
polymer composites.
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