Characterization of the interaction of nitric oxide/nitrogen dioxide with the polymer surfaces in ECMO devices

IF 2.6 4区化学 Q3 POLYMER SCIENCE

Journal of Polymer Research Pub Date : 2024-08-20 DOI:10.1007/s10965-024-04109-x

Moritz Köglmaier, Thilo Joost, Matthias Kronseder, Werner Kunz

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Abstract

In this work, the interactions between nitric oxide (NO)/nitrogen dioxide (NO₂) and the polymer materials of a gas exchanger system used in an extracorporeal membrane oxygenation (ECMO) setting are characterized. FTIR-ATR, XPS, and SEM were used to analyze the effects of the gas treatment. The polymer materials used in the gas exchanger system consisted of polymethylpentene (PMP) hollow fiber membranes, inlet/outlet caps made of methyl methacrylate acrylonitrile butadiene styrene (MABS), casting material consisting of polyurethane (PU), and the gas hoses made of polyvinyl chloride (PVC). Gas treatment with NO and NO₂ was conducted, with exposure times ranging from 30 min to 10 days. The gas concentrations range from 80 to 1000 ppm in the case of NO₂ and a maximum of 10,000 ppm in the case of NO. The formation of nitro and nitrate ester groups and nitric acid (HNO3) adsorption on the polymers’ surface was observed using FTIR-ATR and XPS. The investigations showed that these effects depend on exposure time and gas concentration. The alterations persisted over more extended periods. The XPS measurements showed that the reaction only occurred exclusively on the surface of the polymers. The recorded SEM images showed no macroscopic changes in the surface structures of the polymers.

Graphical Abstract

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一氧化氮/二氧化氮与 ECMO 设备中聚合物表面相互作用的特性分析

本研究对一氧化氮（NO）/二氧化氮（NO2）与体外膜氧合（ECMO）环境中使用的气体交换系统的聚合物材料之间的相互作用进行了表征。傅立叶变换红外-原子吸收光谱（FTIR-ATR）、XPS 和扫描电镜用于分析气体处理的影响。气体交换系统中使用的聚合物材料包括聚甲基戊烯（PMP）中空纤维膜、由甲基丙烯酸甲酯-丙烯腈-丁二烯-苯乙烯（MABS）制成的入口/出口盖、由聚氨酯（PU）组成的浇注材料以及由聚氯乙烯（PVC）制成的气体软管。使用 NO 和 NO2 进行气体处理，暴露时间从 30 分钟到 10 天不等。二氧化氮的气体浓度为 80 至 1000 ppm，氮氧化物的气体浓度最高为 10,000 ppm。使用傅立叶变换红外-原子吸收光谱（FTIR-ATR）和 XPS 观察了聚合物表面硝基和硝酸酯基的形成以及硝酸（HNO3）的吸附情况。研究表明，这些影响取决于暴露时间和气体浓度。这种变化持续的时间更长。XPS 测量显示，反应只发生在聚合物表面。记录的 SEM 图像显示聚合物的表面结构没有发生宏观变化。

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来源期刊

Journal of Polymer Research 化学-高分子科学

CiteScore

4.70

自引率

7.10%

发文量

472

审稿时长

3.6 months

期刊介绍： Journal of Polymer Research provides a forum for the prompt publication of articles concerning the fundamental and applied research of polymers. Its great feature lies in the diversity of content which it encompasses, drawing together results from all aspects of polymer science and technology. As polymer research is rapidly growing around the globe, the aim of this journal is to establish itself as a significant information tool not only for the international polymer researchers in academia but also for those working in industry. The scope of the journal covers a wide range of the highly interdisciplinary field of polymer science and technology, including: polymer synthesis; polymer reactions; polymerization kinetics; polymer physics; morphology; structure-property relationships; polymer analysis and characterization; physical and mechanical properties; electrical and optical properties; polymer processing and rheology; application of polymers; supramolecular science of polymers; polymer composites.