Comparison of indicators for assessing wasting among children younger than 5 years: a longitudinal study in northern Kenya

Calistus Wilunda, Faith Thuita, Bonventure Mwangi, Valerie L Flax, Chessa K Lutter, Linda Adair, Dickson Amugsi, Hazel Odhiambo, Esther Anono, Albert Webale, Gillian Chepkwony, Stephen Ekiru, Elizabeth Kimani-Murage, Estelle Sidze
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Abstract

Mid-upper arm circumference (MUAC) or weight-for-height/length Z-score (WHZ) are recommended in wasting diagnosis, but there are discrepancies between these indicators in identifying children as wasted. We compared the extent to which WHZ, MUAC, MUAC-for-age Z-score (MAZ) identify the same children as wasted and assessed the predictors of discordance and concordance in wasting diagnosis by these indicators using data from a longitudinal study of children younger than 3 years at recruitment in Turkana and Samburu counties. Wasting prevalence was consistently lower based on MUAC than WHZ and MAZ. Compared to WHZ, MAZ had higher sensitivity than MUAC, with the sensitivity of MAZ increasing and MUAC decreasing with age. Both indicators had high specificity. WHZ had a better agreement with MAZ than MUAC in wasting diagnosis. Older children were less likely to be classified as wasted by MUAC alone or by both MUAC and WHZ but were more likely to be classified as wasted by WHZ alone, MAZ alone or by both MAZ and WHZ. Compared to girls, boys were less likely to be classified as wasted by MUAC alone but more likely to be classified as wasted by WHZ alone. Stunted children were more likely to be classified as wasted by MUAC alone, MAZ alone, both MUAC and WHZ, and both MAZ and WHZ but not by WHZ alone. Classifications of wasting based on WHZ, MAZ, and MUAC are age, sex, and stunting status dependent. Compared to WHZ, MAZ is a more reliable and valid indicator than MUAC in these settings.
五岁以下儿童消瘦评估指标的比较:肯尼亚北部的一项纵向研究
中上臂围(MUAC)或体重身高Z值(WHZ)被推荐用于消瘦诊断,但这些指标在确定儿童消瘦方面存在差异。我们利用图尔卡纳县和桑布鲁县招募的 3 岁以下儿童的纵向研究数据,比较了 WHZ、MUAC、MUAC-年龄 Z 值(MAZ)在多大程度上能识别出相同的消瘦儿童,并评估了这些指标在消瘦诊断中的不一致和一致的预测因素。以MUAC为基础的消瘦发生率一直低于WHZ和MAZ。与 WHZ 相比,MAZ 的灵敏度高于 MUAC,随着年龄的增长,MAZ 的灵敏度会增加,而 MUAC 则会降低。这两个指标的特异性都很高。在消瘦诊断方面,WHZ与MAZ的一致性优于MUAC。年龄较大的儿童不太可能仅根据MUAC或同时根据MUAC和WHZ被归类为消瘦,但更有可能仅根据WHZ、MAZ或同时根据MAZ和WHZ被归类为消瘦。与女童相比,男童被归类为消瘦的可能性较小,但被归类为消瘦的可能性较大。发育迟缓儿童更有可能仅根据MUAC、MAZ、MUAC和WHZ、MAZ和WHZ被归类为消瘦,而不是仅根据WHZ被归类为消瘦。根据 WHZ、MAZ 和 MUAC 进行的消瘦分类与年龄、性别和发育迟缓状况有关。在这些情况下,与 WHZ 相比,MAZ 是比 MUAC 更可靠、更有效的指标。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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