Episodic memory impairment and its influencing factors in individuals with autism spectrum disorder: systematic review and meta-analysis

IF 3.5 3区 医学 Q1 CLINICAL NEUROLOGY
Kangjie Geng, Yan Wang, Wangqian Fu, Siting Chen, Yuqi Yang
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引用次数: 0

Abstract

Individuals with autism spectrum disorders (ASD) are considered to experience difficulties with episodic memory (EM), while studies on EM in ASD have shown inconsistent results. A meta-analysis of 65 episodic memory studies with a combined sample size of 1652 individuals with ASD and 1626 typically developing individuals was conducted to analyze factors that may affect EM in ASD. The results showed that ASD had a significant medium to large effect size decrease in EM ability. Age period, task type, and reporting method significantly reduced the observed heterogeneity while EM type did not reduce the observed heterogeneity. The results of the meta-regression revealed that it was verbal IQ rather than full-scale IQ that was significantly correlated with EM in individuals with ASD. These findings suggest that individuals with ASD have reduced EM abilities and the potential factors is still needed to be explored.

Abstract Image

自闭症谱系障碍患者的外显记忆障碍及其影响因素:系统回顾与荟萃分析
自闭症谱系障碍(ASD)患者被认为在外显记忆(EM)方面存在困难,而对ASD患者外显记忆的研究结果却不一致。为了分析可能影响自闭症谱系障碍患者外显记忆的因素,我们对 65 项外显记忆研究进行了荟萃分析,这些研究的样本量分别为 1652 名自闭症谱系障碍患者和 1626 名发育正常的患者。结果表明,ASD患者的EM能力有明显的中度到高度的下降。年龄段、任务类型和报告方法显著降低了观察到的异质性,而EM类型并未降低观察到的异质性。元回归的结果显示,在 ASD 患者中,与 EM 显著相关的是言语智商而非全面智商。这些研究结果表明,ASD患者的EM能力下降,其潜在因素仍有待探索。
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来源期刊
CiteScore
8.80
自引率
4.30%
发文量
154
审稿时长
6-12 weeks
期刊介绍: The original papers published in the European Archives of Psychiatry and Clinical Neuroscience deal with all aspects of psychiatry and related clinical neuroscience. Clinical psychiatry, psychopathology, epidemiology as well as brain imaging, neuropathological, neurophysiological, neurochemical and moleculargenetic studies of psychiatric disorders are among the topics covered. Thus both the clinician and the neuroscientist are provided with a handy source of information on important scientific developments.
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