Chemical warfare agent countermeasures based on macrocycle supramolecular chemistry

IF 10.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Science China Chemistry Pub Date : 2024-09-04 DOI:10.1007/s11426-024-2217-9

Junyi Chen, Yahan Zhang, Chunju Li, Qingbin Meng

引用次数: 0

Abstract

Given that chemical warfare agents (CWAs) pose some of the largest threats to humankind, social stability, and world peace, considerable attention has been drawn to the development of the corresponding detection, decontamination, and treatment techniques. The versatile functionality and distinctive recognition potency of macrocycles enable their customized design for specific tasks, such as chemical sensing, catalysis, or separation. Hence, supramolecular materials are well suited for the establishment of CWA countermeasures. Herein, we summarize the recent progress in the development of macrocycle-based materials for counteracting several representative CWAs, including nerve, blister, blood, incapacitating, choking, and irritating agents, providing a foundation for further advances in this field and fostering practical translational terms.

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基于大循环超分子化学的化学战剂对策

鉴于化学战剂（CWAs）对人类、社会稳定和世界和平构成的最大威胁，相应的检测、去污和处理技术的开发备受关注。由于大环具有多功能性和独特的识别能力，因此可以针对特定任务（如化学传感、催化或分离）进行定制设计。因此，超分子材料非常适合建立 CWA 对策。在此，我们总结了最近在开发基于大环的材料以对抗几种具有代表性的 CWA 方面取得的进展，这些 CWA 包括神经、水疱、血液、致残、窒息和刺激性毒剂，为这一领域的进一步发展奠定了基础，并促进了实用转化。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Science China Chemistry CHEMISTRY, MULTIDISCIPLINARY-

CiteScore

14.40

自引率

7.30%

发文量

3787

审稿时长

2.2 months

期刊介绍： Science China Chemistry, co-sponsored by the Chinese Academy of Sciences and the National Natural Science Foundation of China and published by Science China Press, publishes high-quality original research in both basic and applied chemistry. Indexed by Science Citation Index, it is a premier academic journal in the field. Categories of articles include: Highlights. Brief summaries and scholarly comments on recent research achievements in any field of chemistry. Perspectives. Concise reports on thelatest chemistry trends of interest to scientists worldwide, including discussions of research breakthroughs and interpretations of important science and funding policies. Reviews. In-depth summaries of representative results and achievements of the past 5–10 years in selected topics based on or closely related to the research expertise of the authors, providing a thorough assessment of the significance, current status, and future research directions of the field.