anti-Dihydroxylation of olefins enabled by in situ generated peroxyacetic acid

IF 9.3 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Green Chemistry Pub Date : 2024-09-05 DOI:10.1039/d4gc03540b

Michael Tapera, Mohit Chotia, Jan Lukas Mayer-Figge, Adrián Gómez-Suárez, Stefan F. Kirsch

引用次数: 0

Abstract

Herein, we report a general and green protocol for the anti-dihydroxylation of unactivated alkenes. Combining H₂O₂ and acetic acid at 50 °C results in the formation of peroxyacetic acid, which enables the efficient synthesis of a wide range of anti 1,2-diols in moderate to good yields without the need for hazardous solvents or expensive transition metals as catalysts.

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利用原位生成的过氧乙酸实现烯烃的反二羟基化

在此，我们报告了一种用于未活化烯烃反二羟基化的通用绿色方案。将 H2O2 和乙酸在 50 °C的温度下结合会生成过氧乙酸，过氧乙酸能以中等到良好的产率高效合成各种抗 1,2-二醇，而无需使用有害溶剂或昂贵的过渡金属作为催化剂。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Green Chemistry 化学-化学综合

CiteScore

16.10

自引率

7.10%

发文量

677

审稿时长

1.4 months

期刊介绍： Green Chemistry is a journal that provides a unique forum for the publication of innovative research on the development of alternative green and sustainable technologies. The scope of Green Chemistry is based on the definition proposed by Anastas and Warner (Green Chemistry: Theory and Practice, P T Anastas and J C Warner, Oxford University Press, Oxford, 1998), which defines green chemistry as the utilisation of a set of principles that reduces or eliminates the use or generation of hazardous substances in the design, manufacture and application of chemical products. Green Chemistry aims to reduce the environmental impact of the chemical enterprise by developing a technology base that is inherently non-toxic to living things and the environment. The journal welcomes submissions on all aspects of research relating to this endeavor and publishes original and significant cutting-edge research that is likely to be of wide general appeal. For a work to be published, it must present a significant advance in green chemistry, including a comparison with existing methods and a demonstration of advantages over those methods.