Nanocarriers for nutraceutical delivery: A miniaturized revolution in health

IF 5.45 Q1 Physics and Astronomy

Nano-Structures & Nano-Objects Pub Date : 2024-09-06 DOI:10.1016/j.nanoso.2024.101321

Rajashri B. Sawant, Sonali P. Nikam, Arpita Roy, Ashish Kumar, Osama A. Mohammed, Kuldeep Sharma, Ashutosh Kumar Rai, Amit Roy, Ashish Gaur, Rajan Verma

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Abstract

With the development of nanocarriers, especially in the area of nutraceutical delivery, the rapidly expanding field of nanotechnology has brought in a new age of health and well-being. The revolutionary potential of nanocarriers to improve the stability, bioavailability, and effectiveness of nutraceutical substances is discussed in this review paper. It started with outlining the difficulties that conventional nutraceutical delivery systems have, such as their low solubility and restricted absorption, which frequently obstruct their therapeutic advantages. The various types of nanocarriers which act as nutraceuticals includes liposomes, lipids, and polymer-based materials also highlight of their special qualities and how they get around the problems outlined. Recent developments in nanocarrier technology are critically analyzed to show how these tiny particles may be designed to offer enhanced protection against bioactive compounds and targeted, controlled release. Here toxicity issues and international guidelines compliance while examining safety and regulatory factors relevant to the use of nanocarriers in nutraceuticals has also been discussed. This review concludes with a prospective outlook on the use of nanocarriers in nutraceuticals going ahead, highlighting the possibility of tailored nutrition and the significance of new developments in maintaining and averting illness. This review provides the present status and future prospects of nanocarrier technology in the improvement of nutraceutical delivery by merging recent research findings and expert perspectives.

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用于营养保健品输送的纳米载体：健康领域的微型化革命

随着纳米载体的发展，特别是在营养保健品递送领域的发展，迅速扩展的纳米技术领域带来了一个健康和福祉的新时代。本综述论文讨论了纳米载体在提高营养保健物质的稳定性、生物利用度和有效性方面的革命性潜力。本文首先概述了传统营养保健品给药系统存在的困难，如溶解度低、吸收受限等，这些困难经常阻碍其治疗优势的发挥。作为营养保健品的各类纳米载体包括脂质体、脂类和聚合物基材料，这些载体还强调了它们的特质以及如何解决上述问题。对纳米载体技术的最新发展进行了批判性分析，以说明如何设计这些微小颗粒来加强对生物活性化合物的保护以及有针对性的控制释放。此外，还讨论了毒性问题和遵守国际准则的问题，同时研究了与营养保健品中使用纳米载体相关的安全和监管因素。本综述最后对纳米载体在营养保健品中的应用进行了展望，强调了定制营养的可能性以及新发展在维持和避免疾病方面的意义。本综述结合最新研究成果和专家观点，介绍了纳米载体技术在改善营养保健品递送方面的现状和未来前景。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nano-Structures & Nano-Objects Physics and Astronomy-Condensed Matter Physics

CiteScore

9.20

自引率

0.00%

发文量

审稿时长

22 days

期刊介绍： Nano-Structures & Nano-Objects is a new journal devoted to all aspects of the synthesis and the properties of this new flourishing domain. The journal is devoted to novel architectures at the nano-level with an emphasis on new synthesis and characterization methods. The journal is focused on the objects rather than on their applications. However, the research for new applications of original nano-structures & nano-objects in various fields such as nano-electronics, energy conversion, catalysis, drug delivery and nano-medicine is also welcome. The scope of Nano-Structures & Nano-Objects involves: -Metal and alloy nanoparticles with complex nanostructures such as shape control, core-shell and dumbells -Oxide nanoparticles and nanostructures, with complex oxide/metal, oxide/surface and oxide /organic interfaces -Inorganic semi-conducting nanoparticles (quantum dots) with an emphasis on new phases, structures, shapes and complexity -Nanostructures involving molecular inorganic species such as nanoparticles of coordination compounds, molecular magnets, spin transition nanoparticles etc. or organic nano-objects, in particular for molecular electronics -Nanostructured materials such as nano-MOFs and nano-zeolites -Hetero-junctions between molecules and nano-objects, between different nano-objects & nanostructures or between nano-objects & nanostructures and surfaces -Methods of characterization specific of the nano size or adapted for the nano size such as X-ray and neutron scattering, light scattering, NMR, Raman, Plasmonics, near field microscopies, various TEM and SEM techniques, magnetic studies, etc .