Telomere dynamics as mediators of gut microbiota–host interactions

IF 13 1区 生物学 Q1 CELL BIOLOGY
Michael L. Pepke, Søren B. Hansen, Morten T. Limborg
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引用次数: 0

Abstract

The highly proliferative gut tissue exhibits rapid telomere shortening with systemic effects on the host organism. Recent studies have demonstrated a bidirectionality in interactions between intestinal telomere length dynamics and the composition and activity of the gut microbiome thus linking processes of inflammation, dysbiosis and aging across different vertebrate species.

端粒动力学是肠道微生物与宿主相互作用的媒介
高度增殖的肠道组织表现出端粒快速缩短,并对宿主机体产生系统性影响。最近的研究表明,肠道端粒长度动态与肠道微生物组的组成和活性之间存在双向互动,从而将不同脊椎动物物种的炎症、菌群失调和衰老过程联系起来。
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来源期刊
Trends in Cell Biology
Trends in Cell Biology 生物-细胞生物学
CiteScore
32.00
自引率
0.50%
发文量
160
审稿时长
61 days
期刊介绍: Trends in Cell Biology stands as a prominent review journal in molecular and cell biology. Monthly review articles track the current breadth and depth of research in cell biology, reporting on emerging developments and integrating various methods, disciplines, and principles. Beyond Reviews, the journal features Opinion articles that follow trends, offer innovative ideas, and provide insights into the implications of new developments, suggesting future directions. All articles are commissioned from leading scientists and undergo rigorous peer-review to ensure balance and accuracy.
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