Obesity in Pediatric Hidradenitis Suppurativa: A Scoping Review

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-09-12 DOI:10.1111/pde.15746

Shanti Mehta, Dea Metko, Joseph M. Lam

引用次数: 0

Abstract

The relationship between HS and obesity, while well established in adult patients, has drawn increased attention in pediatric patients given the rising prevalence of pediatric obesity worldwide. This review aims to consolidate existing evidence of the relationship between HS and obesity in the pediatric population and to hypothesize about reasons for an association between the two conditions. Our cohort comprised 2911 patients with a mean age of 11.4 years at the age of onset of HS, and based on body mass index (BMI), 42.3% of patients were classified as obese (BMI > 30), and 14% were overweight (BMI 25–29.9). Our findings indicate an association between obesity and HS in pediatric patients, which may be explained through numerous mechanisms, including shared genetic factors, hereditary relationships, and the impact of HS on adolescents’ quality of life.

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小儿化脓性扁桃体炎患者的肥胖问题：范围界定综述

HS 与肥胖之间的关系虽然在成人患者中已得到充分证实，但由于全球范围内儿科肥胖症的发病率不断上升，因此儿科患者也越来越受到关注。本综述旨在整合现有证据，说明 HS 与肥胖在儿科人群中的关系，并假设这两种疾病之间存在关联的原因。根据体重指数（BMI），42.3%的患者被归类为肥胖（BMI 30），14%为超重（BMI 25-29.9）。我们的研究结果表明，儿科患者的肥胖与 HS 之间存在关联，这可能是由多种机制造成的，包括共同的遗传因素、遗传关系以及 HS 对青少年生活质量的影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.