Generalised tetanus in a cat successfully treated with magnesium sulphate and dexmedetomidine

IF 0.3 Q4 VETERINARY SCIENCES
Marzia Moretti, Angelica Botto, Maria Stella Calabria, Marco Pelizzola, Elisa Bortolami
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引用次数: 0

Abstract

A 4‐year‐old, neutered male domestic short‐haired cat was presented with an abdominal injury, severe extensor rigidity of all limbs and sardonic facial expression. The cat was diagnosed with tetanus and antibiotics, and antiemetics and analgesics were administered. In order to provide myorelaxation, in addition to midazolam, a supraphysiologic dose of magnesium sulphate was infused intravenously at a constant rate of 10 mg/kg/h, after a loading dose of 70 mg/kg; serum magnesium and ionic calcium were measured daily. During hospitalisation, the cat showed hypersensitivity to stimuli, tetanic seizures, hyperthermia and autonomic dysfunction, presenting as severe hypertension, sinus and ventricular tachycardia. An intravenous infusion of dexmedetomidine (1 ± 0.5 µg/kg/h) improved haemodynamic parameters and attenuated muscle spasms, and its administration was continued for 96 h without adverse reactions. The magnesium infusion was maintained for 11 days without toxicity, except for a mild hypocalcaemia. The cat's clinical signs gradually improved and the patient was discharged on day 28.
用硫酸镁和右美托咪定成功治疗一只猫的全身性破伤风
一只 4 岁的绝育雄性家养短毛猫腹部受伤,四肢严重僵硬,面部表情呆滞。该猫被诊断为破伤风,医生为其注射了抗生素、止吐药和镇痛药。为了让猫咪肌肉放松,除了咪达唑仑外,还以 10 毫克/千克/小时的恒定速度静脉注射了超生理剂量的硫酸镁,之前的负荷剂量为 70 毫克/千克;每天测量血清镁和离子钙。住院期间,该猫出现了对刺激过敏、四肢抽搐、高热和自主神经功能障碍,表现为严重的高血压、窦性心动过速和室性心动过速。静脉输注右美托咪定(1 ± 0.5 µg/kg/h)改善了血流动力学参数并减轻了肌肉痉挛,持续用药 96 小时未出现不良反应。除了轻微的低钙血症外,镁输注维持了 11 天,未出现毒性反应。猫的临床症状逐渐好转,患者于第 28 天出院。
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来源期刊
Veterinary Record Case Reports
Veterinary Record Case Reports Veterinary-Veterinary (all)
CiteScore
0.50
自引率
33.30%
发文量
266
期刊介绍: Vet Record Case Reports is an online resource that publishes articles in all fields of veterinary medicine and surgery so that veterinary professionals, researchers and others can easily find important information on both common and rare conditions. Articles may be about a single animal, herd, flock or other group of animals managed together. Common cases that present a diagnostic, ethical or management challenge, or that highlight aspects of mechanisms of injury, pharmacology or histopathology are deemed of particular educational value. All articles are peer reviewed and copy edited before publication.
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