Impact of upgrading from a 25-cm to a 30-cm z-axis field of view digital PET/CT in a pediatric hospital

IF 2.1 3区医学 Q2 PEDIATRICS

Pediatric Radiology Pub Date : 2024-09-11 DOI:10.1007/s00247-024-06049-6

Joseph G. Meier, Andrew T. Trout, Nadeen Abu Ata, Susan E. Sharp, Christopher G. Anton, Elanchezhian Somasundaram, Samuel L. Brady

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引用次数: 0

Abstract

Background

Increased positron emission tomography (PET) scanner z-axis coverage provides an opportunity in pediatrics to reduce dose, anesthesia, or repeat scans due to motion.

Objective

Recently, our digital PET scanner was upgraded from a 25-cm to a 30-cm z-axis coverage. We compare the two systems through National Electrical Manufacturing Association (NEMA) testing and evaluation of paired images from patients scanned on both systems.

Materials and methods

NEMA testing and a retrospective review of pediatric patients who underwent clinically indicated 18F-fluorodeoxyglucose (FDG) PET computed tomography (PET/CT) on both systems with unchanged acquisition parameters were performed. Image quality was assessed with liver signal to noise ratio (SNR-liver) and contrast to noise ratio (CNR) in the thigh muscle and liver with results compared with an unpaired t-test. Three readers independently reviewed paired (25 cm and 30 cm) images from the same patient, blinded to scanner configuration.

Results

Expansion to 30 cm increased system sensitivity to 29.8% (23.4 cps/kBq to 30.4 cps/kBq). Seventeen patients (6 male/11 female, median age 12.5 (IQR 8.3–15.0) years, median weight 53.7 (IQR 34.2–68.7) kg) were included. SNR-liver and CNR increased by 35.1% (IQR 19.0–48.4%) and 43.1% (IQR 6.2–50.2%) (P-value <0.001), respectively. All readers preferred images from the 30-cm configuration. A median of 1 (IQR 1–1) for fewer bed positions was required with the 30-cm configuration allowing a median of 91 (IQR 47–136) s for shorter scans.

Conclusion

Increasing z-axis coverage from 25 to 30 cm on a current-generation digital PET scanner significantly improved PET system performance and patient image quality, and reduced scan duration.

Abstract Image

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一家儿科医院将数字 PET/CT 的 Z 轴视场从 25 厘米升级到 30 厘米的影响

背景增加正电子发射断层扫描（PET）扫描仪的 Z 轴覆盖范围为儿科提供了一个机会，可以减少剂量、麻醉或因运动而导致的重复扫描.目标最近，我们的数字 PET 扫描仪的 Z 轴覆盖范围从 25 厘米升级到了 30 厘米。我们通过美国国家电气制造协会（NEMA）测试和对两套系统扫描患者的配对图像进行评估，对两套系统进行了比较。材料和方法我们对两套系统进行了NEMA测试，并在采集参数不变的情况下，对接受了有临床指征的18F-氟脱氧葡萄糖（FDG）正电子发射计算机断层扫描（PET/CT）的儿科患者进行了回顾性审查。用肝脏信噪比（SNR-liver）和大腿肌肉及肝脏对比度与噪声比（CNR）评估图像质量，并用非配对 t 检验比较结果。三位读者在扫描仪配置盲区内独立审查了来自同一患者的成对（25 厘米和 30 厘米）图像。结果扩展到 30 厘米后，系统灵敏度提高了 29.8%（23.4 cps/kBq 至 30.4 cps/kBq）。共纳入 17 名患者（6 男/11 女，中位年龄 12.5（IQR 8.3-15.0）岁，中位体重 53.7（IQR 34.2-68.7）公斤）。肝脏 SNR 和 CNR 分别增加了 35.1%（IQR 19.0-48.4%）和 43.1%（IQR 6.2-50.2%）（P 值为 0.001）。所有读者都喜欢 30 厘米配置的图像。结论在当前一代数字 PET 扫描仪上，将 Z 轴覆盖范围从 25 厘米增加到 30 厘米可显著提高 PET 系统性能和患者图像质量，并缩短扫描时间。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Pediatric Radiology 医学-核医学

CiteScore

4.40

自引率

17.40%

发文量

300

审稿时长

3-6 weeks

期刊介绍： Official Journal of the European Society of Pediatric Radiology, the Society for Pediatric Radiology and the Asian and Oceanic Society for Pediatric Radiology Pediatric Radiology informs its readers of new findings and progress in all areas of pediatric imaging and in related fields. This is achieved by a blend of original papers, complemented by reviews that set out the present state of knowledge in a particular area of the specialty or summarize specific topics in which discussion has led to clear conclusions. Advances in technology, methodology, apparatus and auxiliary equipment are presented, and modifications of standard techniques are described. Manuscripts submitted for publication must contain a statement to the effect that all human studies have been reviewed by the appropriate ethics committee and have therefore been performed in accordance with the ethical standards laid down in an appropriate version of the 1964 Declaration of Helsinki. It should also be stated clearly in the text that all persons gave their informed consent prior to their inclusion in the study. Details that might disclose the identity of the subjects under study should be omitted.