(Diethylamino)sulfur trifluoride (DAST)-mediated oxidation of benzylic alcohols and amines to carbonyl compounds

IF 1.8 3区化学 Q3 CHEMISTRY, ORGANIC

Synthetic Communications Pub Date : 2024-08-29 DOI:10.1080/00397911.2024.2397499

引用次数: 0

Abstract

We report an efficient protocol for oxidation of primary/secondary benzyl alcohols and benzylamines to produce corresponding aldehydes or ketones. Our unified method involves the use of commercially available (diethylamino)sulfur trifluoride (DAST) as a reagent combined with DMSO as solvent and oxidant. The reaction provided corresponding carbonyl compounds in good to excellent yields with high purity and in short reaction times.

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(三氟化硫（DAST）介导的苄醇和胺氧化成羰基化合物的过程

我们报告了一种高效的一级/二级苄醇和苄胺氧化方法，可生成相应的醛或酮。我们的统一方法包括使用市售的（二乙基氨基）三氟化硫（DAST）作为试剂，结合二甲基亚砜（DMSO）作为溶剂和氧化剂。该反应提供了相应的羰基化合物，收率好，纯度高，反应时间短。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Synthetic Communications 化学-有机化学

CiteScore

4.40

自引率

4.80%

发文量

156

审稿时长

4.3 months

期刊介绍： Synthetic Communications presents communications describing new methods, reagents, and other synthetic work pertaining to organic chemistry with sufficient experimental detail to permit reported reactions to be repeated by a chemist reasonably skilled in the art. In addition, the Journal features short, focused review articles discussing topics within its remit of synthetic organic chemistry.