Introduction and overview on autogenous Platelet concentrates

IF 17.5 1区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE
Marc Quirynen, Anton Sculean, J. Blanco, Hom‐Lay Wang, Nikos Donos
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Abstract

This special issue on autologous platelet concentrates (APCs) provides clinicians with an overview on the current understanding of the use of these biomaterials for soft and hard‐tissue regeneration. The included papers summarize scientific evidence and the clinical findings, presented in simple tables that outline potential benefits including Patient Reported Outcome Measures (PROMs). This approach enables clinicians to assess clinical relevance and researchers to identify significant gaps in the literature. The first part provides a comprehensive summary of the basic science surrounding APC, with particular focus on their preparation methods. Clear recommendations are outlined, which are crucial for obtaining high‐quality APCs, alongside an exploration of how APCs may influence both soft and hard tissue healing processes. Part 2 delves into the clinical evidence for the potential benefits of APCs across a range of applications: alveolar ridge preservation, sinus floor elevation, periodontal plastic surgery, guided tissue regeneration, guided bone regeneration, the healing of Medication‐Related Osteonecrosis of the Jaw (MRONJ), and endodontic surgery. In the part 3, the discussion turns to the effects of APCs on the healing of extra‐oral wounds, including diabetic foot ulcers, venous leg ulcers, pressure injuries, burns, and more. For those clinicians persuaded by the evidence, the fourth section offers a detailed, step‐by‐step flowchart for each treatment modality, providing a clear guide for clinical application.
自体血小板浓缩物简介和概述
本期特刊介绍自体血小板浓缩物 (APC),向临床医生概述目前对这些生物材料用于软组织和硬组织再生的认识。收录的论文总结了科学证据和临床发现,并以简单的表格呈现,概述了包括患者报告结果指标 (PROM) 在内的潜在益处。这种方法能让临床医生评估临床相关性,让研究人员找出文献中的重大空白。第一部分全面总结了有关 APC 的基础科学,尤其关注其制备方法。在探讨 APC 如何影响软组织和硬组织愈合过程的同时,还概述了对获得高质量 APC 至关重要的明确建议。第二部分深入探讨了 APCs 在一系列应用中潜在益处的临床证据:牙槽脊保存、窦底抬高、牙周整形手术、引导组织再生、引导骨再生、药物相关性颌骨坏死 (MRONJ) 的愈合以及牙髓手术。在第 3 部分中,讨论将转向 APC 对口外伤口愈合的影响,包括糖尿病足溃疡、静脉腿部溃疡、压伤、烧伤等。对于那些被证据说服的临床医生,第四部分为每种治疗方式提供了详细的分步流程图,为临床应用提供了明确的指导。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Periodontology 2000
Periodontology 2000 医学-牙科与口腔外科
CiteScore
34.10
自引率
2.20%
发文量
62
审稿时长
>12 weeks
期刊介绍: Periodontology 2000 is a series of monographs designed for periodontists and general practitioners interested in periodontics. The editorial board selects significant topics and distinguished scientists and clinicians for each monograph. Serving as a valuable supplement to existing periodontal journals, three monographs are published annually, contributing specialized insights to the field.
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