Blood profile indicates central inflammation in frontotemporal lobar degeneration

IF 28.2 1区医学 Q1 CLINICAL NEUROLOGY

Nature Reviews Neurology Pub Date : 2024-09-12 DOI:10.1038/s41582-024-01021-2

Ian Fyfe

引用次数: 0

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血液特征显示额颞叶变性的中枢炎症

新研究发现，促炎性血清特征与额颞叶变性（Frontotemporal lobar degeneration，FLTD）有关，这增加了用血液生物标记物评估痴呆症患者神经炎症的可能性。研究人员分析了214名患有FTLD相关综合征的患者和29名健康人血清中的细胞因子。他们的分析确定了一种与FLTD相关的促炎细胞因子特征。这种血清特征的强烈表达与更严重的中枢神经炎症（PET 成像显示小胶质细胞活化）和更短的存活期有关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nature Reviews Neurology 医学-临床神经学

CiteScore

29.90

自引率

0.80%

发文量

138

审稿时长

6-12 weeks

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