Adaptive deep brain stimulation shows promise

IF 28.2 1区医学 Q1 CLINICAL NEUROLOGY

Nature Reviews Neurology Pub Date : 2024-09-12 DOI:10.1038/s41582-024-01019-w

Ian Fyfe

引用次数: 0

Abstract

Adaptive deep brain stimulation (DBS) improves motor symptoms and quality of life in people with Parkinson disease compared with continuous DBS, the results of a pilot trial suggest. The study included four people with Parkinson disease, each of whom received continuous and adaptive DBS at different times to enable comparison of the effects. Adaptive stimulation was personalized according to motor cortical signals that were identified as biomarkers of fluctuations in motor function. When compared with the effects of continuous stimulation in each individual, adaptive stimulation reduced the time with motor symptoms and improved the participants’ quality of life with respect to normal daily activities.

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自适应深部脑刺激技术大有可为

一项试验结果表明，与持续性脑深部刺激（DBS）相比，自适应脑深部刺激（DBS）可改善帕金森病患者的运动症状和生活质量。这项研究包括四名帕金森病患者，他们分别在不同的时间接受了连续性和自适应 DBS 刺激，以便对效果进行比较。自适应刺激根据运动皮质信号进行个性化设计，这些信号被确定为运动功能波动的生物标志物。与每个人接受连续刺激的效果相比，自适应刺激缩短了出现运动症状的时间，提高了参与者在正常日常活动方面的生活质量。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nature Reviews Neurology 医学-临床神经学

CiteScore

29.90

自引率

0.80%

发文量

138

审稿时长

6-12 weeks

期刊介绍： Nature Reviews Neurology aims to be the premier source of reviews and commentaries for the scientific and clinical communities we serve. We want to provide an unparalleled service to authors, referees, and readers, and we work hard to maximize the usefulness and impact of each article. The journal publishes Research Highlights, Comments, News & Views, Reviews, Consensus Statements, and Perspectives relevant to researchers and clinicians working in the field of neurology. Our broad scope ensures that the work we publish reaches the widest possible audience. Our articles are authoritative, accessible, and enhanced with clearly understandable figures, tables, and other display items. This page gives more detail about the aims and scope of the journal.

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