{"title":"Outside Back Cover: Volume 3 Issue 5","authors":"","doi":"10.1002/idm2.12221","DOIUrl":null,"url":null,"abstract":"<p><b>Outside Back Cover</b>: The cover image of doi:10.1002/idm2.12181 shows a magnified view of an osteochondral defect in the left femur with an implanted 3D-bioprinted biphasic scaffold. The scaffold consists of a cartilage layer (blue) and a subchondral bone layer (purple), created using multicellular bioprinting technology. In the cartilage layer, GelMA loaded with articular chondrocytes (ACs, yellow) and bone marrow mesenchymal stem cells (BMSCs, red) interacts to maintain the phenotype of ACs and promote BMSC chondrogenesis. In the subchondral bone layer, GelMA/Sr-CSH (yellow fibers) with BMSCs releases bioactive ions (Ca, Si, Sr) that enhance BMSC osteogenesis and stimulate ACs. GelMA supports osteochondral interface reconstruction.\n\n <figure>\n <div><picture>\n <source></source></picture><p></p>\n </div>\n </figure>\n </p>","PeriodicalId":100685,"journal":{"name":"Interdisciplinary Materials","volume":null,"pages":null},"PeriodicalIF":24.5000,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/idm2.12221","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Interdisciplinary Materials","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/idm2.12221","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, PHYSICAL","Score":null,"Total":0}
引用次数: 0
Abstract
Outside Back Cover: The cover image of doi:10.1002/idm2.12181 shows a magnified view of an osteochondral defect in the left femur with an implanted 3D-bioprinted biphasic scaffold. The scaffold consists of a cartilage layer (blue) and a subchondral bone layer (purple), created using multicellular bioprinting technology. In the cartilage layer, GelMA loaded with articular chondrocytes (ACs, yellow) and bone marrow mesenchymal stem cells (BMSCs, red) interacts to maintain the phenotype of ACs and promote BMSC chondrogenesis. In the subchondral bone layer, GelMA/Sr-CSH (yellow fibers) with BMSCs releases bioactive ions (Ca, Si, Sr) that enhance BMSC osteogenesis and stimulate ACs. GelMA supports osteochondral interface reconstruction.
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