Efficacy and feasibility of web-based ACT-Enhanced behavioral treatment for skin picking in adults: A randomized waitlist-controlled trial

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-09-06 DOI:10.1016/j.jocrd.2024.100909

Emily M. Bowers, Leila K. Capel, Mercedes G. Woolley, Aubry Barnes, Michael P. Twohig, Michael E. Levin

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Abstract

Skin picking disorder is a chronic repetitive condition that impacts daily functioning and causes significant distress. Acceptance and commitment therapy (ACT) enhanced behavioral training (A-EBT) has shown promise in targeting skin picking symptoms but is not widely disseminated among providers. This study examines the efficacy and feasibility of an eight-week fully-automated online A-EBT program for skin picking disorder. Participants with skin picking disorder (N = 84) were randomized into either an online intervention (n = 43) or a waitlist control (n = 41). All participants completed self-report assessments at baseline, mid-, post-intervention, and 1-month follow-up. Analyses used multilevel linear modeling with the full intent-to-treat sample. Results demonstrated statistically stronger improvements from baseline to 1-month follow-up in the intervention condition compared to waitlist for skin picking symptoms (SMD = 0.90), skin picking-related psychological flexibility (SMD = −0.82), and well-being (SMD = −0.31), with no significant effects on distress. Treatment effects were maintained at one-month follow-up, with 29.0% of intervention participants meeting responder status, compared to 0.1% of waitlist participants. High usability and acceptability scores provide preliminary evidence of its feasibility as a fully automated intervention. These findings suggest an automated online A-EBT program may be an effective and scalable treatment for individuals with skin picking disorder.

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基于网络的 ACT 增强行为疗法治疗成人皮肤搔痒的有效性和可行性：随机候选对照试验

抠皮症是一种慢性重复性疾病，会影响日常功能并造成严重困扰。接受与承诺疗法（ACT）增强行为训练（A-EBT）已显示出针对抠皮症状的治疗效果，但并未在医疗机构中广泛传播。本研究探讨了为期八周的全自动在线 A-EBT 项目对抠皮症的疗效和可行性。患有皮肤搔痒症的参与者（84 人）被随机分配到在线干预（43 人）或候补对照组（41 人）中。所有参与者都在基线、中期、干预后和 1 个月的随访中完成了自我报告评估。分析采用了多层次线性模型，对全部意向治疗样本进行了分析。结果表明，从基线到1个月随访，干预条件与等待名单相比，在皮肤抠取症状（SMD = 0.90）、皮肤抠取相关心理灵活性（SMD = -0.82）和幸福感（SMD = -0.31）方面都有显著改善，而在痛苦方面没有明显效果。治疗效果在一个月的随访中得以保持，29.0%的干预参与者达到了应答状态，而等待者中只有0.1%达到了应答状态。较高的可用性和可接受性得分初步证明了其作为全自动干预的可行性。这些研究结果表明，对于皮肤搔痒症患者来说，自动在线A-EBT程序可能是一种有效且可推广的治疗方法。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.