Hip contact force pathways in total hip replacement differ between patients and activities of daily living

IF 2.4 3区 医学 Q3 BIOPHYSICS
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Abstract

One of the main causes of implant failure and revision surgery in total hip replacement (THR) is aseptic loosening often caused by the accumulation of wear debris arising between the contact surfaces of the acetabular cup and femoral head during activities of daily living (ADL’s). However, limited information is available regarding the contact force pathways between these two surfaces during specific ADL’s. In this study, through musculoskeletal modelling, we aimed to estimate the orientation of the hip contact force pathway on the acetabular cup. One hundred and thirty-two THR patients underwent motion capture analysis whilst undertaking locomotor and non-locomotor ADL’s. Musculoskeletal simulations were performed to calculate contact force pathways using inverse dynamics analysis. We then qualitatively compared differences in the contact force pathways between patients and between ADL’s. Walking resulted in a typical figure-of-eight pattern, with the peak contact forces occurring in the superior-anterior area of the cup. The non-locomotive activities such as stand up, sit down and squat had a more linear shape, spanning across the superior-posterior quarter of the cup. Our results showed a large inter-patient variability in the shape and location of the contact force pathway.

There is a distinct difference in the location and shape of the pathway between locomotor and non-locomotor activities and this could result in different wear accumulations. These results could enhance our understanding why revision rates vary across the population and could inform the development of personalised implant design.

全髋关节置换术的髋关节接触力路径因患者和日常生活活动而异
全髋关节置换术(THR)植入失败和翻修手术的主要原因之一是无菌性松动,通常是由于日常生活(ADL)中髋臼杯和股骨头接触面之间的磨损碎屑堆积造成的。然而,关于这两个表面在特定日常活动中的接触力路径的信息却很有限。在这项研究中,我们通过肌肉骨骼建模,旨在估算髋臼杯上髋关节接触力路径的方向。132 名 THR 患者在进行运动和非运动 ADL 时接受了运动捕捉分析。我们进行了肌肉骨骼模拟,利用反动力学分析计算接触力路径。然后,我们定性比较了不同患者之间以及不同日常活动之间接触力路径的差异。步行产生了典型的 "八 "字形模式,接触力峰值出现在杯口的上前方区域。而起立、坐下和下蹲等非定位活动则呈现出更多的线性形状,横跨髋臼杯的上后四分之一。我们的研究结果表明,患者之间在接触力路径的形状和位置上存在很大的差异。这些结果可以加深我们对不同人群翻修率不同原因的理解,并为个性化种植体设计的开发提供参考。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of biomechanics
Journal of biomechanics 生物-工程:生物医学
CiteScore
5.10
自引率
4.20%
发文量
345
审稿时长
1 months
期刊介绍: The Journal of Biomechanics publishes reports of original and substantial findings using the principles of mechanics to explore biological problems. Analytical, as well as experimental papers may be submitted, and the journal accepts original articles, surveys and perspective articles (usually by Editorial invitation only), book reviews and letters to the Editor. The criteria for acceptance of manuscripts include excellence, novelty, significance, clarity, conciseness and interest to the readership. Papers published in the journal may cover a wide range of topics in biomechanics, including, but not limited to: -Fundamental Topics - Biomechanics of the musculoskeletal, cardiovascular, and respiratory systems, mechanics of hard and soft tissues, biofluid mechanics, mechanics of prostheses and implant-tissue interfaces, mechanics of cells. -Cardiovascular and Respiratory Biomechanics - Mechanics of blood-flow, air-flow, mechanics of the soft tissues, flow-tissue or flow-prosthesis interactions. -Cell Biomechanics - Biomechanic analyses of cells, membranes and sub-cellular structures; the relationship of the mechanical environment to cell and tissue response. -Dental Biomechanics - Design and analysis of dental tissues and prostheses, mechanics of chewing. -Functional Tissue Engineering - The role of biomechanical factors in engineered tissue replacements and regenerative medicine. -Injury Biomechanics - Mechanics of impact and trauma, dynamics of man-machine interaction. -Molecular Biomechanics - Mechanical analyses of biomolecules. -Orthopedic Biomechanics - Mechanics of fracture and fracture fixation, mechanics of implants and implant fixation, mechanics of bones and joints, wear of natural and artificial joints. -Rehabilitation Biomechanics - Analyses of gait, mechanics of prosthetics and orthotics. -Sports Biomechanics - Mechanical analyses of sports performance.
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