The epigenomic matrix of tissue-specific immune memory

IF 25.5 1区医学 Q1 IMMUNOLOGY

Immunity Pub Date : 2024-09-10 DOI:10.1016/j.immuni.2024.08.009

Sarah Adamo, Marcus Buggert

引用次数: 0

Abstract

Tissue-resident memory CD8⁺ T cells serve as a first-line defense against many pathogens. In this issue of Immunity, Buquicchio et al. unveil the epigenomic landscapes of virus-specific CD8⁺ T cell subsets, highlighting common and organ-specific regulators driving their differentiation.

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组织特异性免疫记忆的表观基因组基质

组织驻留记忆 CD8+ T 细胞是抵御许多病原体的第一道防线。在本期《免疫》杂志上，Buquicchio 等人揭示了病毒特异性 CD8+ T 细胞亚群的表观基因组图谱，强调了驱动其分化的共同和器官特异性调控因子。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Immunity 医学-免疫学

CiteScore

49.40

自引率

2.20%

发文量

205

审稿时长

6 months

期刊介绍： Immunity is a publication that focuses on publishing significant advancements in research related to immunology. We encourage the submission of studies that offer groundbreaking immunological discoveries, whether at the molecular, cellular, or whole organism level. Topics of interest encompass a wide range, such as cancer, infectious diseases, neuroimmunology, autoimmune diseases, allergies, mucosal immunity, metabolic diseases, and homeostasis.