The inflammaging clock strikes IL-11!

IF 25.5 1区医学 Q1 IMMUNOLOGY

Immunity Pub Date : 2024-09-10 DOI:10.1016/j.immuni.2024.08.010

Saad Khan, Veronica Chang, Daniel A. Winer

引用次数: 0

Abstract

Chronic inflammation is considered a hallmark of aging. In a recent issue of Nature, Widjaja et al. examined genetic and pharmacologic inhibition of interleukin (IL)-11 on aging pathology and found that inhibiting IL-11 signaling increases lifespan and healthspan in mice.

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发炎时钟敲响了 IL-11！

慢性炎症被认为是衰老的标志。在最近一期《自然》杂志上，Widjaja 等人研究了遗传和药物抑制白细胞介素（IL）-11 对衰老病理学的影响，发现抑制 IL-11 信号传导可延长小鼠的寿命，延长其健康寿命。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Immunity 医学-免疫学

CiteScore

49.40

自引率

2.20%

发文量

205

审稿时长

6 months

期刊介绍： Immunity is a publication that focuses on publishing significant advancements in research related to immunology. We encourage the submission of studies that offer groundbreaking immunological discoveries, whether at the molecular, cellular, or whole organism level. Topics of interest encompass a wide range, such as cancer, infectious diseases, neuroimmunology, autoimmune diseases, allergies, mucosal immunity, metabolic diseases, and homeostasis.