Impact of Interventions on Medication Adherence in Patients With Coexisting Diabetes and Hypertension

IF 3 3区医学 Q2 HEALTH CARE SCIENCES & SERVICES

Health Expectations Pub Date : 2024-09-09 DOI:10.1111/hex.70010

Pauline Tendai Maniki, Betty Bouad Chaar, Parisa Aslani

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Abstract

Background

The coexistence of diabetes and hypertension is prevalent due to shared risk factors. Pharmacological treatment has been reported to be effective in managing both conditions. However, treatment effectiveness depends on the extent to which a patient adheres to their treatment. Poor adherence to long-term treatment for chronic diseases is a growing global problem of significant magnitude. Several interventions have been developed to help improve medication adherence in patients with coexisting diabetes and hypertension. This review aimed to determine the characteristics of these interventions and their impact on medication adherence.

Methods

A systematic review of the literature was conducted using the PRISMA guidelines and registered in the PROSPERO International Registry of Systematic Reviews. Studies were searched in the databases CINAHL, Embase and Medline to identify relevant articles published during 2012–2023. The search concepts included ‘medication adherence’, ‘hypertension’, ‘diabetes’ and ‘intervention’. Studies were included if they were in English and evaluated the impact of an intervention aimed at promoting adherence to medications for both diabetes and hypertension.

Results

Seven studies met the inclusion criteria, with five demonstrating a statistically significant improvement in medication adherence. Of the five studies that improved medication adherence, four were multifaceted and one was a single-component intervention. All successful interventions addressed at least two factors influencing non-adherence. Patient education was the foundation of most of the successful interventions, supported by other strategies, such as follow-ups and reminders.

Conclusion

Multifaceted interventions that also included patient education had a positive impact on medication adherence in patients with coexisting diabetes and hypertension. Improving adherence in patients with coexisting diabetes and hypertension requires a multipronged approach that considers the range of factors impacting medication-taking.

Patient or Public Contribution

This systematic review provides comprehensive insights into the benefits of patient-centred approaches in intervention development and strengthening. Such patient involvement ensures that medication adherence interventions are more relevant, acceptable and effective, ultimately leading to better health outcomes and more meaningful patient engagement in healthcare research.

Abstract Image

查看原文本刊更多论文

干预措施对糖尿病和高血压并存患者坚持用药的影响。

背景：由于共同的风险因素，糖尿病和高血压并存的情况十分普遍。据报道，药物治疗可有效控制这两种疾病。然而，治疗效果取决于患者坚持治疗的程度。慢性病长期治疗的依从性差是一个日益严重的全球性问题。目前已开发出多种干预措施，帮助改善糖尿病和高血压并存患者的服药依从性。本综述旨在确定这些干预措施的特点及其对坚持服药的影响：采用 PRISMA 指南对文献进行了系统性综述，并在 PROSPERO 国际系统性综述注册中心进行了注册。研究在 CINAHL、Embase 和 Medline 数据库中进行检索，以确定 2012-2023 年间发表的相关文章。检索概念包括 "用药依从性"、"高血压"、"糖尿病 "和 "干预"。纳入的研究必须是英文研究，并且评估了旨在促进糖尿病和高血压患者坚持服药的干预措施的影响：结果：有七项研究符合纳入标准，其中五项研究表明，坚持服药的情况在统计学上有显著改善。在改善服药依从性的五项研究中，四项是多方面干预，一项是单一成分干预。所有成功的干预措施都解决了至少两个影响不坚持用药的因素。患者教育是大多数成功干预措施的基础，并辅以其他策略，如随访和提醒：结论：包括患者教育在内的多层面干预措施对糖尿病和高血压并存患者的服药依从性有积极影响。改善糖尿病和高血压并存患者的服药依从性需要多管齐下，考虑影响服药的一系列因素：本系统综述全面阐述了以患者为中心的方法在制定和加强干预措施方面的益处。此类患者参与可确保服药依从性干预措施更具相关性、可接受性和有效性，最终带来更好的健康结果，并使患者更有意义地参与医疗保健研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Health Expectations 医学-公共卫生、环境卫生与职业卫生

CiteScore

5.20

自引率

9.40%

发文量

251

审稿时长

>12 weeks

期刊介绍： Health Expectations promotes critical thinking and informed debate about all aspects of patient and public involvement and engagement (PPIE) in health and social care, health policy and health services research including: • Person-centred care and quality improvement • Patients'' participation in decisions about disease prevention and management • Public perceptions of health services • Citizen involvement in health care policy making and priority-setting • Methods for monitoring and evaluating participation • Empowerment and consumerism • Patients'' role in safety and quality • Patient and public role in health services research • Co-production (researchers working with patients and the public) of research, health care and policy Health Expectations is a quarterly, peer-reviewed journal publishing original research, review articles and critical commentaries. It includes papers which clarify concepts, develop theories, and critically analyse and evaluate specific policies and practices. The Journal provides an inter-disciplinary and international forum in which researchers (including PPIE researchers) from a range of backgrounds and expertise can present their work to other researchers, policy-makers, health care professionals, managers, patients and consumer advocates.