Efectividad de la resonancia magnética cerebral en el diagnóstico precoz y caracterización de las demencias: revisión sistemática

IF 2.6 4区医学 Q1 MEDICINE, GENERAL & INTERNAL

Medicina Clinica Pub Date : 2024-09-07 DOI:10.1016/j.medcli.2024.05.028

Ana María Ruiz Tornero , Esther E. García Carpintero , Begoña Rodríguez Ortiz de Salazar

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Abstract

Introduction

Magnetic resonance imaging (MRI) is a frequently used test in the diagnosis of dementia. The objective was to evaluate its effectiveness for the early diagnosis of dementia in patients with mild cognitive impairment (MCI).

Material and methods

Original studies were selected from systematic reviews between 2011 and 2021, according to PRISMA 2020 criteria. QUADAS-2 and GRADE tools were used, and a meta-analysis was performed.

Results

Final selection of 23 articles. Patient selection and index test had a high probability of bias. The certainty of the evidence was very low. In the hippocampus, sensitivity was 0.62 (95%CI 0.48-0.79) and specificity 0.70 (95%CI 0.55-0.80). In the temporal lobe, sensitivity was 0.65 (range 0.45) and specificity 0.69 (range 0.32).

Conclusions

There is insufficient evidence to recommend routine brain MRI for the early diagnosis of dementia in patients with MCI.

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脑磁共振成像在痴呆症早期诊断和定性方面的有效性；系统性综述。

简介磁共振成像（MRI）是诊断痴呆症的常用检查方法。本文旨在评估磁共振成像在早期诊断轻度认知障碍（MCI）患者痴呆症方面的有效性：根据 PRISMA 2020 标准，从 2011 年至 2021 年的系统综述中筛选出原创研究。采用 QUADAS-2 和 GRADE 工具，并进行荟萃分析：最终筛选出 23 篇文章。患者选择和指标测试存在较高的偏倚概率。证据的确定性很低。在海马区，灵敏度为 0.62（95%CI 0.48-0.79），特异性为 0.70（95%CI 0.55-0.80）。在颞叶，敏感性为 0.65（范围 0.45），特异性为 0.69（范围 0.32）：没有足够的证据建议将常规脑磁共振成像用于MCI患者痴呆症的早期诊断。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Medicina Clinica 医学-医学：内科

CiteScore

3.10

自引率

5.10%

发文量

295

审稿时长

22 days

期刊介绍： Medicina Clínica, fundada en 1943, es una publicación quincenal dedicada a la promoción de la investigación y de la práctica clínica entre los especialistas de la medicina interna, así como otras especialidades. Son características fundamentales de esta publicación el rigor científico y metodológico de sus artículos, la actualidad de los temas y, sobre todo, su sentido práctico, buscando siempre que la información sea de la mayor utilidad en la práctica clínica.