Diffuse Large B-Cell Lymphoma in a Cynomolgus Monkey

IF 0.8 4区农林科学 Q3 VETERINARY SCIENCES

Journal of Medical Primatology Pub Date : 2024-09-08 DOI:10.1111/jmp.12734

Heling Li, Long Zhang, Zhigang Chen, Faliang Zong, Baohong Tian, Xinglong Chen, Deli Liu, Qing Ning, Hong Wang

引用次数: 0

Abstract

A captive 17-year-old male cynomolgus monkey (Macaca fascicularis) developed diffuse large B-cell lymphoma (DLBCL). This was the first report of DLBCL presenting with a mandible mass and violation of the paranasal sinus in a cynomolgus monkey. The neoplasm showed marked microscopical malignant aspects. Immunohistochemical staining showed strong positive expression of CD20. These features may contribute to the diagnosis and therapeutics of DLBCL in NHPs.

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绒猴弥漫性大 B 细胞淋巴瘤

一只圈养的17岁雄性猴（Macaca fascicularis）患上了弥漫性大B细胞淋巴瘤（DLBCL）。这是首次报道猕猴的弥漫性大 B 细胞淋巴瘤伴有下颌骨肿块并侵犯副鼻窦。肿瘤在显微镜下显示出明显的恶性特征。免疫组化染色显示 CD20 呈强阳性表达。这些特征可能有助于NHPs中DLBCL的诊断和治疗。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Medical Primatology 生物-动物学

CiteScore

1.40

自引率

42.90%

发文量

审稿时长

6 months

期刊介绍： The Journal of Medical Primatology publishes research on non-human primates as models to study, prevent, and/or treat human diseases; subjects include veterinary medicine; morphology, physiology, reproductive biology, central nervous system, and cardiovascular diseases; husbandry, handling, experimental methodology, and management of non-human primate colonies and laboratories; non-human primate wildlife management; and behaviour and sociology as related to medical conditions and captive non-human primate needs. Published material includes: Original Manuscripts - research results; Case Reports - scientific documentation of a single clinical study; Short Papers - case histories, methodologies, and techniques of particular interest; Letters to the Editor - opinions, controversies and sporadic scientific observations; Perspectives – opinion piece about existing research on a particular topic; Minireviews – a concise review of existing literature; Book Reviews by invitation; Special Issues containing selected papers from specialized meetings; and Editorials and memoriams authored by the Editor-in-Chief.