The Use of Bone Substitute Blocks in Minimally Invasive Orthognathic Surgery: Enhancing Jaw Stability and Healing.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-09-09 DOI:10.1097/SCS.0000000000010628

Jonathas Daniel Paggi Claus, Matheus Spinella Almeida, Hugo Jose Correia Lopes

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Abstract

This study aims to evaluate the use of bone substitute blocks (BSBs) in minimally invasive orthognathic surgery for the maxilla, mandible, and chin, highlighting their impact on jaw stability and bone healing. A retrospective analysis was conducted on 47 consecutive patients (33 females, 14 males; mean age: 27 y) who underwent bimaxillary advancement surgery. Procedures employed the minimally invasive orthognathic surgery approach. Bovine BSBs (Bio-Oss Collagen) were used to fill gaps in all cases. Postoperative follow-up included computed tomography scans at immediate and 1-year intervals. All patients achieved the desired clinical outcomes without complications such as wound dehiscence, infection, or nonunion. Visual Analog Scale scores indicated high levels of bone formation, with mean scores of 9.1 in the chin, 8.5 in the maxilla, and 7.9 in the mandible. The study supports the routine use of BSBs in orthognathic surgeries, though further research is needed to validate these findings and explore long-term outcomes.

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在微创正颌外科手术中使用骨替代块：增强下颌稳定性和愈合。

本研究旨在评估骨替代块（BSB）在上颌骨、下颌骨和下巴微创正颌手术中的使用情况，强调其对颌骨稳定性和骨愈合的影响。我们对 47 名连续接受双颌前突手术的患者（33 名女性，14 名男性；平均年龄：27 岁）进行了回顾性分析。手术采用微创正颌外科手术方法。所有病例均使用牛 BSB（Bio-Oss 胶原）填充间隙。术后随访包括即刻和一年的计算机断层扫描。所有患者都达到了预期的临床效果，没有出现伤口开裂、感染或不愈合等并发症。视觉模拟量表的评分显示骨形成的水平很高，下巴的平均评分为 9.1 分，上颌骨为 8.5 分，下颌骨为 7.9 分。这项研究支持在正颌手术中常规使用 BSB，但还需要进一步的研究来验证这些发现并探讨长期效果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.