Generalised Blisters and Respiratory distress: A Case of Bullous Systemic Lupus Erythematosus.

IF 1.9 4区 医学 Q3 DERMATOLOGY
Clinical, Cosmetic and Investigational Dermatology Pub Date : 2024-09-02 eCollection Date: 2024-01-01 DOI:10.2147/CCID.S484441
Mingyuan Ren, Yijia He, Jianzhong Zhang, Jinfang Zhang, Guoqiang Zhang
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引用次数: 0

Abstract

Tjalma's syndrome is a benign combination of ascites, pleural effusion, and elevated CA-125 occurring in patients with systemic lupus erythematosus. Reports of Tjalma's syndrome are scarce. An elevated CA-125 level often suggests the possibility of the presence of a malignant tumor. We report a case of generalised erythema and blisters with pruritus, massive unilateral pleural effusion and elevated CA-125. This patient was finally diagnosed with bullous systemic lupus erythematosus after exclusion of tumour and other maculopapular disorders. We hope that this particular case may provide a more comprehensive and novel diagnostic idea of systemic lupus erythematosus and pleural effusion, avoiding unnecessary anxiety, laboratory tests and surgical interventions.

全身性水疱和呼吸困难:大疱性系统性红斑狼疮病例。
Tjalma综合征是系统性红斑狼疮患者出现腹水、胸腔积液和CA-125升高的良性综合征。有关 Tjalma 综合征的报道很少。CA-125 水平升高通常提示存在恶性肿瘤的可能性。我们报告了一例全身红斑和水疱伴瘙痒、大量单侧胸腔积液和 CA-125 升高的病例。在排除了肿瘤和其他斑丘疹性疾病后,该患者最终被诊断为大疱性系统性红斑狼疮。我们希望这个特殊病例能为系统性红斑狼疮和胸腔积液提供一个更全面、更新颖的诊断思路,避免不必要的焦虑、实验室检查和手术干预。
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来源期刊
CiteScore
2.80
自引率
4.30%
发文量
353
审稿时长
16 weeks
期刊介绍: Clinical, Cosmetic and Investigational Dermatology is an international, peer-reviewed, open access journal that focuses on the latest clinical and experimental research in all aspects of skin disease and cosmetic interventions. Normal and pathological processes in skin development and aging, their modification and treatment, as well as basic research into histology of dermal and dermal structures that provide clinical insights and potential treatment options are key topics for the journal. Patient satisfaction, preference, quality of life, compliance, persistence and their role in developing new management options to optimize outcomes for target conditions constitute major areas of interest. The journal is characterized by the rapid reporting of clinical studies, reviews and original research in skin research and skin care. All areas of dermatology will be covered; contributions will be welcomed from all clinicians and basic science researchers globally.
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