Highly sensitive dual-functional all-dielectric biosensor for hemoglobin and cancer detection

IF 3 3区计算机科学 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC

Aeu-International Journal of Electronics and Communications Pub Date : 2024-09-02 DOI:10.1016/j.aeue.2024.155504

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引用次数: 0

Abstract

This paper is the first demonstration of a dual-functional metasurface (DFM) based on all-dielectric materials for biosensing applications. The proposed biosensor possesses a unique capability to switch between polarization conversion and absorber functionalities owing to the phase changing properties of VO₂. Accordingly, the sensor works in two modes: a highly sensitive reflective cross-polarization converter mode (4.38 - 5.08 THz) and an absorber mode (4.36 - 5.96 THz), both of which hold significant promise for the detection of hemoglobin and cancer cells, respectively. When VO₂ is in the insulating state, the reflective cross-polarization converter function of this biosensor exhibits exceptional sensitivity of 3.08 THz/RIU for hemoglobin detection. This is the highest sensitivity among the existing THz based biosensors. Likewise, the same biosensor transforms into an absorber when VO₂ is in the conducting state, offering an impressive sensitivity of 2.93 THz/RIU for detection of cancerous cells. The all-dielectric based DFM biosensor also provides a high degree of angular stability, providing stable response for incident angles of up to 60° for both its polarization converter and absorber functions.

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用于检测血红蛋白和癌症的高灵敏度双功能全介电生物传感器

本文首次展示了一种基于全介电材料的双功能元表面（DFM），可用于生物传感应用。由于 VO2 的相变特性，所提出的生物传感器具有在偏振转换和吸收功能之间切换的独特能力。因此，该传感器可在两种模式下工作：高灵敏度的反射式交叉极化转换器模式（4.38 - 5.08 THz）和吸收器模式（4.36 - 5.96 THz），这两种模式分别在检测血红蛋白和癌细胞方面大有可为。当 VO2 处于绝缘状态时，这种生物传感器的反射式交叉极化转换器功能在检测血红蛋白方面表现出 3.08 THz/RIU 的超高灵敏度。这是现有太赫兹生物传感器中灵敏度最高的。同样，当 VO2 处于导电状态时，同一生物传感器会转变为吸收器，在检测癌细胞时可提供令人印象深刻的 2.93 THz/RIU 灵敏度。基于全介质的 DFM 生物传感器还具有高度的角度稳定性，其偏振转换器和吸收器功能可在入射角度高达 60° 时提供稳定响应。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Aeu-International Journal of Electronics and Communications 工程技术-电信学

CiteScore

6.90

自引率

18.80%

发文量

292

审稿时长

4.9 months

期刊介绍： AEÜ is an international scientific journal which publishes both original works and invited tutorials. The journal''s scope covers all aspects of theory and design of circuits, systems and devices for electronics, signal processing, and communication, including: signal and system theory, digital signal processing network theory and circuit design information theory, communication theory and techniques, modulation, source and channel coding switching theory and techniques, communication protocols optical communications microwave theory and techniques, radar, sonar antennas, wave propagation AEÜ publishes full papers and letters with very short turn around time but a high standard review process. Review cycles are typically finished within twelve weeks by application of modern electronic communication facilities.