The relationship between structural properties of frontal cortical regions and response inhibition in 6–14-year-old children

IF 2.2 3区心理学 Q3 NEUROSCIENCES

Brain and Cognition Pub Date : 2024-09-05 DOI:10.1016/j.bandc.2024.106220

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引用次数: 0

Abstract

Development of attentional skills and inhibitory control rely on maturational changes in the brain across childhood and youth. However, both brain anatomy and different components of attention and inhibition show notable individual variation. Research on ADHD and inhibitory training and control have shown that variations in the thickness and surface area of particularly inferior cortical structures are associated with attentional control. However, the intricacies of how the development of inhibitory control is associated with the anatomical variations beyond the general age- and gender-dependent differences have not been resolved. Here, we sought to address these questions by quantifying the cortical thickness and surface area in frontal cortical regions and inhibitory control using the stop signal task performance in 6–14-year-old children. Our results showed that the thickness of the left medial orbitofrontal cortex and the surface area of the left caudal anterior cingulate were associated with the inhibitory performance, beyond the variance that could be explained by the subjects’ age and gender. The results highlight the importance of factoring in anatomical variations when following attentional development and the importance of evaluating multiple anatomical measures when aiming to link the properties of cortical structures with variations in cognitive performance.

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6-14 岁儿童额叶皮层区域的结构特性与反应抑制之间的关系。

注意能力和抑制控制能力的发展依赖于整个童年和青年时期大脑的成熟变化。然而，大脑解剖结构以及注意力和抑制能力的不同组成部分都显示出明显的个体差异。有关多动症和抑制训练与控制的研究表明，特别是下皮层结构的厚度和表面积的变化与注意力控制有关。然而，除了一般的年龄和性别差异外，抑制控制能力的发展如何与解剖学变化相关联的复杂问题尚未得到解决。在此，我们试图通过量化额叶皮质区域的皮质厚度和表面积以及 6-14 岁儿童的停止信号任务表现来解决这些问题。我们的研究结果表明，左侧内侧眶额皮层的厚度和左侧尾状前扣带回的表面积与抑制表现有关，超出了受试者年龄和性别所能解释的差异。研究结果强调了在跟踪注意力发展时考虑解剖学变化的重要性，以及在将皮层结构的特性与认知表现的变化联系起来时评估多种解剖学测量的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Brain and Cognition 医学-神经科学

CiteScore

4.60

自引率

0.00%

发文量

审稿时长

6 months

期刊介绍： Brain and Cognition is a forum for the integration of the neurosciences and cognitive sciences. B&C publishes peer-reviewed research articles, theoretical papers, case histories that address important theoretical issues, and historical articles into the interaction between cognitive function and brain processes. The focus is on rigorous studies of an empirical or theoretical nature and which make an original contribution to our knowledge about the involvement of the nervous system in cognition. Coverage includes, but is not limited to memory, learning, emotion, perception, movement, music or praxis in relationship to brain structure or function. Published articles will typically address issues relating some aspect of cognitive function to its neurological substrates with clear theoretical import, formulating new hypotheses or refuting previously established hypotheses. Clinical papers are welcome if they raise issues of theoretical importance or concern and shed light on the interaction between brain function and cognitive function. We welcome review articles that clearly contribute a new perspective or integration, beyond summarizing the literature in the field; authors of review articles should make explicit where the contribution lies. We also welcome proposals for special issues on aspects of the relation between cognition and the structure and function of the nervous system. Such proposals can be made directly to the Editor-in-Chief from individuals interested in being guest editors for such collections.