Hantavirus: Preliminary assessment of lateral flow immune assay prototypes to detect IgM and IgG antibodies

IF 2.1 4区医学 Q3 INFECTIOUS DISEASES

Diagnostic microbiology and infectious disease Pub Date : 2024-09-02 DOI:10.1016/j.diagmicrobio.2024.116521

João Pedro Tôrres Guimarães , Matheus Bernardes Torres Fogaça , Rodrigo Scaliante Moura , Marcelo Mendonça , Fabricio Rochedo Conceição , João Bosco Lima Gimaque , Talita Heleny Pacheco de Almeida , Cláudia Abrain , Maria Paula Gomes Mourão , Luiz Tadeu Moraes Figueiredo , Mariane Martins Araújo Stefani , Samira Bührer-Sékula

引用次数: 0

Abstract

Three lateral flow immunoassay prototypes developed to detect IgM, IgG and IgM/IgG antibodies against Hantavirus were evaluated. A total of 163 samples were tested: 10 from Hantavirus patients, 103 from related diseases, and 50 from healthy controls. The prototypes exhibited 100 % sensitivity, 97.5 % to 99.3 % specificity, indicating promising improved diagnosis.

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汉坦病毒：检测 IgM 和 IgG 抗体的侧流免疫测定原型的初步评估。

对开发的用于检测汉坦病毒 IgM、IgG 和 IgM/IgG 抗体的三种侧流免疫测定原型进行了评估。共检测了 163 份样本：10 份来自汉坦病毒患者，103 份来自相关疾病，50 份来自健康对照组。这些原型的灵敏度为 100%，特异度为 97.5%至 99.3%，表明有望改善诊断。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Diagnostic microbiology and infectious disease 医学-传染病学

CiteScore

5.30

自引率

3.40%

发文量

149

审稿时长

56 days

期刊介绍： Diagnostic Microbiology and Infectious Disease keeps you informed of the latest developments in clinical microbiology and the diagnosis and treatment of infectious diseases. Packed with rigorously peer-reviewed articles and studies in bacteriology, immunology, immunoserology, infectious diseases, mycology, parasitology, and virology, the journal examines new procedures, unusual cases, controversial issues, and important new literature. Diagnostic Microbiology and Infectious Disease distinguished independent editorial board, consisting of experts from many medical specialties, ensures you extensive and authoritative coverage.