An overview on polyurethane-degrading enzymes

IF 12.1 1区 工程技术 Q1 BIOTECHNOLOGY & APPLIED MICROBIOLOGY
Agata Raczyńska , Artur Góra , Isabelle André
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引用次数: 0

Abstract

Polyurethanes (PUR) are durable synthetic polymers widely used in various industries, contributing significantly to global plastic consumption. PUR pose unique challenges in terms of degradability and recyclability, as they are characterised by intricate compositions and diverse formulations. Additives and proprietary structures used in commercial PUR formulations further complicate recycling efforts, making the effective management of PUR waste a daunting task.

In this review, we delve into the complex challenge of enzymatic degradation of PUR, focusing on the structural and functional attributes of both enzymes and PUR. We also present documented native enzymes with reported efficacy in hydrolysing specific bonds within PUR, analysis of these enzyme structures, reaction mechanisms, substrate specificity, and binding site architecture. Furthermore, we propose essential features for the future redesign of enzymes to optimise PUR biodegradation efficiency. By outlining prospective research directions aimed at advancing the field of enzymatic biodegradation of PUR, we aim to contribute to the development of sustainable solutions for managing PUR waste and reducing environmental pollution.

聚氨酯降解酶概述。
聚氨酯(PUR)是一种耐用的合成聚合物,广泛应用于各行各业,对全球塑料消耗量贡献巨大。聚氨酯具有成分复杂、配方多样的特点,因此在降解性和可回收性方面面临着独特的挑战。商用聚氨酯配方中使用的添加剂和专有结构进一步加剧了回收工作的复杂性,使聚氨酯废弃物的有效管理成为一项艰巨的任务。在本综述中,我们将深入探讨聚氨酯酶降解的复杂挑战,重点关注酶和聚氨酯的结构和功能属性。我们还介绍了在水解聚氨酯中的特定键方面具有功效的原生酶的记录,以及对这些酶的结构、反应机制、底物特异性和结合部位结构的分析。此外,我们还提出了未来重新设计酶的基本特征,以优化 PUR 的生物降解效率。通过概述旨在推进聚氨酯酶生物降解领域的前瞻性研究方向,我们希望为聚氨酯废物管理和减少环境污染的可持续解决方案的开发做出贡献。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Biotechnology advances
Biotechnology advances 工程技术-生物工程与应用微生物
CiteScore
25.50
自引率
2.50%
发文量
167
审稿时长
37 days
期刊介绍: Biotechnology Advances is a comprehensive review journal that covers all aspects of the multidisciplinary field of biotechnology. The journal focuses on biotechnology principles and their applications in various industries, agriculture, medicine, environmental concerns, and regulatory issues. It publishes authoritative articles that highlight current developments and future trends in the field of biotechnology. The journal invites submissions of manuscripts that are relevant and appropriate. It targets a wide audience, including scientists, engineers, students, instructors, researchers, practitioners, managers, governments, and other stakeholders in the field. Additionally, special issues are published based on selected presentations from recent relevant conferences in collaboration with the organizations hosting those conferences.
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