Enamel caries lesions, with and without initial cavitation, in relation to anatomical areas of the proximal surface in deciduous molars

IF 2.2 4区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE
Basílio Rodrigues Vieira , Leonardo de Freitas Ferreira , Nathalie Murielly Rolim de Abreu , Frederico Barbosa de Sousa
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引用次数: 0

Abstract

Objective

proximal enamel caries lesions (PEC) are believed to initiate and progress to cavitation below the proximal contact area (PCA), but no evidence exists on the location of initial carious cavitation on the proximal surface with functional PCA. This study aimed to test the association of anatomical areas of the proximal surface with the severity of PEC and the frequency of cavitation in PEC in primary molars

Design

laboratory, observational, transversal study. Exfoliated primary molars (n = 33) with functional PCA (biofilm-free PCA surrounded by biofilm) had their proximal surfaces (one/tooth) divided anatomically into up to nine areas: 3 areas based on the occlusal/cervical PCA boundaries (areas I, II, and III; occluso-cervically) and 3 areas based on the bucco/lingual PCA boundaries (A, B, and C), with area IIB representing the PCA and area IIIB as the sub-PCA (below the PCA). PEC (ICDAS scores 1 and 2–3) and cavitation in PEC were quantified in all areas using stereomicroscopy and microCT. PEC volume was quantified in areas IIB and IIIB under microCT

Results

PEC severity increased occluso-cervically. PCA and sub-PCA presented different PEC severities (higher in sub-PCA) and similar PCE volumes, but the odds of carious cavitation were much higher (Odds ratio = 197.4; 95 % CI: 8.7/4480.7) in the PCA than in the sub-PCA (no cavitation).

Conclusion

PCA presented lower PEC severity and similar PEC volume compared to sub-PCA, but PCA concentrated all cavitations in PEC, supporting a new model for the pathogenesis of PEC.

与脱落磨牙近端表面解剖区域相关的釉质龋损(有无初始龋蚀)。
目的:近端釉质龋损(PEC)被认为是在近端接触区(PCA)以下开始并发展到龋坏的,但没有证据表明近端表面初始龋坏的位置与功能性PCA有关。本研究旨在检验近端表面解剖区域与初级磨牙PEC严重程度和PEC龋蚀频率的关联性。对具有功能性 PCA(无生物膜的 PCA,周围有生物膜)的脱落初级磨牙(n = 33)的近端表面(一颗/颗)进行解剖学划分,最多可分为 9 个区域:其中 3 个区域以咬合/颈部 PCA 边界为基础(区域 I、II 和 III;咬合-颈部),3 个区域以颊面/舌面 PCA 边界为基础(A、B 和 C),区域 IIB 代表 PCA,区域 IIIB 为亚 PCA(位于 PCA 下方)。使用体视显微镜和显微 CT 对所有区域的 PEC(ICDAS 评分 1 和 2-3)和 PEC 中的空洞化进行量化。在显微 CT 下对 IIB 区和 IIIB 区的 PEC 容量进行了量化 结果:PEC 的严重程度在颈锁骨上有所增加。PCA和亚PCA的PEC严重程度不同(亚PCA更高),PCE体积相似,但PCA发生龋齿空洞化的几率(Odds ratio = 197.4; 95 % CI: 8.7/4480.7)远高于亚PCA(无空洞化):结论:与亚PCA相比,PCA的PEC严重程度较低,PEC体积相似,但PCA的所有龋损都集中在PEC,支持PEC发病机制的新模型。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Archives of oral biology
Archives of oral biology 医学-牙科与口腔外科
CiteScore
5.10
自引率
3.30%
发文量
177
审稿时长
26 days
期刊介绍: Archives of Oral Biology is an international journal which aims to publish papers of the highest scientific quality in the oral and craniofacial sciences. The journal is particularly interested in research which advances knowledge in the mechanisms of craniofacial development and disease, including: Cell and molecular biology Molecular genetics Immunology Pathogenesis Cellular microbiology Embryology Syndromology Forensic dentistry
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