Impact of Truenat on TB diagnosis in Nigeria.

IF 1.3 Q4 RESPIRATORY SYSTEM

Public Health Action Pub Date : 2024-09-01 DOI:10.5588/pha.24.0021

R Eneogu, J Olabamiji, A Ihesie, N Nwokoye, K Ochei, P Nwadike, O Salau, Z Munguno, B Odume, A Agbaje, D Nongo, O Oyelaran, W van Germert, L Mupfumi, E Emeka, C Anyaike, E N Ossai

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Abstract

Objective: To evaluate the impact of Truenat assays on the diagnosis of TB at peripheral facilities in Nigeria.

Methods: This was a retrospective cross-sectional study across 34 out of 38 Truenat-implementing facilities in Nigeria. These facilities offer DOTS services. Information on turnaround time (TAT) for TB diagnosis and time to commencement of treatment was obtained. Also, trends in TB case notifications at the facilities 9 months prior to and 9 months during Truenat implementation were compared.

Results: Of 2,335 entries, 70.1% (1,636) were used to determine TAT, while 45.8% (n = 1,070) were used for time to treatment initiation. The median time to diagnosis was <24 hours (IQR 0-1 days). The majority (57.9%) were diagnosed in <24 hours. The median time to treatment initiation was 1.5 days (IQR 0-3). In 9 months before the introduction of Truenat, 8% of 20,424 presumptives evaluated were positive for TB, while during the implementation, 9% of 37,087 presumptives were positive for TB.

Conclusion: Truenat deployment led to an increase in TB and DR-TB case detection in peripheral facilities in Nigeria. It also decreased TAT and time to TB treatment initiation. These have positive implications in the fight against TB, and Truenat is relevant in finding missing TB cases in Nigeria.

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Truenat 对尼日利亚结核病诊断的影响。

目的评估特鲁纳特检测法对尼日利亚周边机构结核病诊断的影响：这是一项回顾性横断面研究，涉及尼日利亚 38 家实施特鲁纳试验的机构中的 34 家。这些机构提供短期直接观察治疗服务。研究获得了结核病诊断周转时间（TAT）和开始治疗时间的信息。此外，还比较了这些机构在实施 Truenat 之前 9 个月和实施期间 9 个月的肺结核病例通报趋势：结果：在 2,335 个病例中，70.1%（1,636 例）用于确定 TAT，45.8%（n = 1,070 例）用于确定开始治疗的时间。诊断时间的中位数为结论：部署 Truenat 提高了尼日利亚外围机构的结核病和 DR-TB 病例检测率。它还缩短了 TAT 和开始结核病治疗的时间。这对抗击结核病具有积极意义，而且 Truenat 对发现尼日利亚的遗漏结核病病例具有重要意义。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Public Health Action RESPIRATORY SYSTEM-

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期刊介绍： Launched on 1 May 2011, Public Health Action (PHA) is an official publication of the International Union Against Tuberculosis and Lung Disease (The Union). It is an open access, online journal available world-wide to physicians, health workers, researchers, professors, students and decision-makers, including public health centres, medical, university and pharmaceutical libraries, hospitals, clinics, foundations and institutions. PHA is a peer-reviewed scholarly journal that actively encourages, communicates and reports new knowledge, dialogue and controversy in health systems and services for people in vulnerable and resource-limited communities — all topics that reflect the mission of The Union, Health solutions for the poor.

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