SPECT/CT imaging of poor sleep quality in people with epilepsy

IF 2.3 3区医学 Q2 BEHAVIORAL SCIENCES

Epilepsy & Behavior Pub Date : 2024-09-04 DOI:10.1016/j.yebeh.2024.110014

Rong Chen , Mengyun Li , Bofei Tan , Sihui Li , Xiaodan Jia , Qing Zhang , Xianrui Xu , Qiang Liu , Zeli Ma , Xuan Li , Ying Wang , Nan Tian , Yanzi Jin , Qing Zhang

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引用次数: 0

Abstract

Purpose

To analyze the characteristics of cerebral blood flow changes of poor sleep quality in people with epilepsy(PWE).

Methods

90 PWE treated in The General Hospital of Ningxia Medical University from December 2021 to September 2023 were divided into poor sleep quality group (PSQG) and good sleep quality group (GSQG) according to the Chinese version of the Pittsburgh Sleep Quality Index (CPSQI), to compare the differences in cerebral perfusion between the two groups of patients, so as to summarize the characteristics of cerebral blood flow changes of poor sleep quality in PWE.

Results

The positive rate of interictal single-photon emission computed tomography/computed tomography (SPECT/CT) was 76.7 %(69/90), which showed localized cerebral hypoperfusion. There was no statistical difference between the two groups of PSQG (N=29) and GSQG (N=61) in terms of the positive rate of SPECT/CT, the number of hypoperfusion foci, and the range of hypoperfusion foci. In PSQG and GSQG, 9 patients(31.0 %) and 6 patients(9.8 %) showed hypoperfusion in the right parietal lobe, respectively, and the difference between the two groups was statistically significant (P=0.017). There was no statistical difference the rate of the interictal epileptiform discharges (IEDs) and the brain area of IEDs in electroencephalography(EEG) between the two groups.

Conclusion

SPECT/CT of poor sleep quality in PWE demonstrated hypoperfusion in the right parietal lobe.

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癫痫患者睡眠质量差的SPECT/CT成像

目的分析睡眠质量差的癫痫患者（PWE）脑血流变化特征。方法根据中国版匹兹堡睡眠质量指数（CPSQI）将2021年12月至2023年9月在宁夏医科大学总医院接受治疗的90例PWE分为睡眠质量差组（PSQG）和睡眠质量好组（GSQG），比较两组患者脑血流灌注的差异，从而总结PWE睡眠质量差的脑血流变化特点。结果发作间期单光子发射计算机断层扫描/计算机断层扫描（SPECT/CT）阳性率为76.7%（69/90），显示局部脑灌注不足。PSQG 组（29 人）和 GSQG 组（61 人）在 SPECT/CT 阳性率、低灌注灶数量和低灌注灶范围方面没有统计学差异。在 PSQG 和 GSQG 中，分别有 9 名患者（31.0%）和 6 名患者（9.8%）出现右顶叶低灌注，两组差异有统计学意义（P=0.017）。两组患者发作间期癫痫样放电（IEDs）发生率和脑电图（EEG）IEDs脑区无统计学差异。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Epilepsy & Behavior 医学-行为科学

CiteScore

5.40

自引率

15.40%

发文量

385

审稿时长

43 days

期刊介绍： Epilepsy & Behavior is the fastest-growing international journal uniquely devoted to the rapid dissemination of the most current information available on the behavioral aspects of seizures and epilepsy. Epilepsy & Behavior presents original peer-reviewed articles based on laboratory and clinical research. Topics are drawn from a variety of fields, including clinical neurology, neurosurgery, neuropsychiatry, neuropsychology, neurophysiology, neuropharmacology, and neuroimaging. From September 2012 Epilepsy & Behavior stopped accepting Case Reports for publication in the journal. From this date authors who submit to Epilepsy & Behavior will be offered a transfer or asked to resubmit their Case Reports to its new sister journal, Epilepsy & Behavior Case Reports.