Design of hexagonal shaped spectroscopy based biosensor for the detection of tuberculosis

IF 5.4 Q1 CHEMISTRY, ANALYTICAL

Sensing and Bio-Sensing Research Pub Date : 2024-08-01 DOI:10.1016/j.sbsr.2024.100682

Rakib Hossen , Md. Selim Hossain , Sadia Afrin Mim , Md. Al-Amin , Sabbir Ahmed , Md. Ashrafuzzaman , Md. Ashiq Salahin , Shuvo Sen

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引用次数: 0

Abstract

A proposal has been made to identify tuberculosis cells using a novel compact sensor based on photonic crystal fiber: PCF in accordance with hexagonal spectroscopy. This proposed structure, which consists of a closely packed hexagonal air hole in the cladding region and a hollow-core area, possesses a very low loss of 6.30 × 10⁻⁸ dB/m and an exceptionally high sensitivity of up to 91.75 % (tuberculosis cell for 1.345). Numerous optical parameters have been identified and assessed, comprised of the numerical aperture, the V-parameter, or normalized frequency (V_eff), and the effective area (A_eff). The operational wavelength range is defined as 0.80–3.0 THz. The numerical investigation of the properties of the proposed TB sensors is performed within the environment of COMSOL Multiphysics (Version 5.3) using FV-FEM stands for the full vector finite element method. PCF sensors composed of hexagonal lattice in a circular form with ZEONEX as the backdrop material is intended to boost the sensitivity response in comparison to the earlier works. Additionally, the sensor that is being displayed achieves a single modality throughout its whole operational wavelength range. This proposed sensor may play a significant role in identifying tuberculosis thanks to its superior sensitivity response and extremely minimal confinement loss. So, it is clearly seen that this sensor could be used to bio-medical sectors with process of terahertz (THz) wave pulse.

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设计基于六角形光谱的结核病检测生物传感器

有人建议使用基于光子晶体光纤的新型紧凑传感器来识别结核病细胞：PCF 与六边形光谱学相结合。这种拟议的结构由包层区域的密布六边形气孔和中空纤芯区域组成，具有 6.30 × 10-8 dB/m 的极低损耗和高达 91.75 % 的超高灵敏度（结核病细胞为 1.345）。已经确定并评估了许多光学参数，包括数值孔径、V 参数或归一化频率 (Veff) 和有效面积 (Aeff)。工作波长范围定义为 0.80-3.0 太赫兹。在 COMSOL Multiphysics（5.3 版）环境下，使用 FV-FEM 表示全矢量有限元法，对所提出的 TB 传感器的特性进行了数值研究。PCF 传感器由圆形六边形晶格组成，以 ZEONEX 为背景材料，旨在提高灵敏度响应。此外，所展示的传感器在其整个工作波长范围内实现了单一模式。由于其卓越的灵敏度响应和极小的封闭损耗，这种拟议的传感器可在识别结核病方面发挥重要作用。因此，我们可以清楚地看到，这种传感器可通过太赫兹（THz）脉冲波用于生物医学领域。

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来源期刊

Sensing and Bio-Sensing Research Engineering-Electrical and Electronic Engineering

CiteScore

10.70

自引率

3.80%

发文量

审稿时长

87 days

期刊介绍： Sensing and Bio-Sensing Research is an open access journal dedicated to the research, design, development, and application of bio-sensing and sensing technologies. The editors will accept research papers, reviews, field trials, and validation studies that are of significant relevance. These submissions should describe new concepts, enhance understanding of the field, or offer insights into the practical application, manufacturing, and commercialization of bio-sensing and sensing technologies. The journal covers a wide range of topics, including sensing principles and mechanisms, new materials development for transducers and recognition components, fabrication technology, and various types of sensors such as optical, electrochemical, mass-sensitive, gas, biosensors, and more. It also includes environmental, process control, and biomedical applications, signal processing, chemometrics, optoelectronic, mechanical, thermal, and magnetic sensors, as well as interface electronics. Additionally, it covers sensor systems and applications, µTAS (Micro Total Analysis Systems), development of solid-state devices for transducing physical signals, and analytical devices incorporating biological materials.