Jung Ho Kim, Jae Eun Seong, Sangmin Ahn, Yongseop Lee, Jung Ah Lee, Jin Young Ahn, Su Jin Jeong, Nam Su Ku, Joon-Sup Yeom, Jun Yong Choi
{"title":"Antiretroviral Therapy during Long-term Surgical Care: 'Exploring Difficult Cases in HIV Clinics' of the Korean Society for AIDS Conference in 2023.","authors":"Jung Ho Kim, Jae Eun Seong, Sangmin Ahn, Yongseop Lee, Jung Ah Lee, Jin Young Ahn, Su Jin Jeong, Nam Su Ku, Joon-Sup Yeom, Jun Yong Choi","doi":"10.3947/ic.2024.0052","DOIUrl":null,"url":null,"abstract":"<p><p>With advancements in antiretroviral therapy (ART), the average lifespan of people with human immunodeficiency virus (HIV) is increasing, as is the number of older adults with HIV. Accordingly, the number of patients with HIV who undergo surgery or require critical care for various reasons is increasing. Since the prognosis of people with HIV depends on the continuous and effective maintenance of ART, there is a need to consider effectively maintaining ART in people with HIV in these conditions. This case involved a 55-year-old patient with well-controlled HIV who received ART and presented to the emergency room with acute abdominal pain. He was diagnosed with extensive bowel infarction and panperitonitis and received critical care in the intensive care unit, including mechanical ventilation and continuous renal replacement therapy. The patient was administered enteral nutrition via a nasogastric tube. The patient subsequently underwent extensive small bowel resection and developed short bowel syndrome. The patient maintained ART during that period. A literature review related to the use of ART under these conditions is included in this study. This case was discussed at the [Exploring Difficult Cases in HIV Clinics] of the Korean Society for AIDS Conference held in 2023.</p>","PeriodicalId":51616,"journal":{"name":"Infection and Chemotherapy","volume":" ","pages":"287-299"},"PeriodicalIF":2.8000,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11458491/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Infection and Chemotherapy","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3947/ic.2024.0052","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/8/1 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"INFECTIOUS DISEASES","Score":null,"Total":0}
引用次数: 0
Abstract
With advancements in antiretroviral therapy (ART), the average lifespan of people with human immunodeficiency virus (HIV) is increasing, as is the number of older adults with HIV. Accordingly, the number of patients with HIV who undergo surgery or require critical care for various reasons is increasing. Since the prognosis of people with HIV depends on the continuous and effective maintenance of ART, there is a need to consider effectively maintaining ART in people with HIV in these conditions. This case involved a 55-year-old patient with well-controlled HIV who received ART and presented to the emergency room with acute abdominal pain. He was diagnosed with extensive bowel infarction and panperitonitis and received critical care in the intensive care unit, including mechanical ventilation and continuous renal replacement therapy. The patient was administered enteral nutrition via a nasogastric tube. The patient subsequently underwent extensive small bowel resection and developed short bowel syndrome. The patient maintained ART during that period. A literature review related to the use of ART under these conditions is included in this study. This case was discussed at the [Exploring Difficult Cases in HIV Clinics] of the Korean Society for AIDS Conference held in 2023.
随着抗逆转录病毒疗法(ART)的发展,人类免疫缺陷病毒(HIV)感染者的平均寿命不断延长,感染 HIV 的老年人也越来越多。因此,因各种原因接受手术或需要重症监护的 HIV 感染者人数也在增加。由于艾滋病病毒感染者的预后取决于持续有效地维持抗逆转录病毒疗法,因此有必要考虑在这些情况下有效维持艾滋病病毒感染者的抗逆转录病毒疗法。本病例涉及一名 55 岁的艾滋病病毒感染者,他接受了抗逆转录病毒疗法,因急性腹痛到急诊就诊。他被诊断为大面积肠梗死和泛腹膜炎,在重症监护室接受了重症监护,包括机械通气和持续肾脏替代治疗。患者通过鼻胃管接受肠内营养。患者随后接受了广泛的小肠切除术,并患上了短肠综合征。在此期间,患者一直坚持抗逆转录病毒疗法。本研究对在这些情况下使用 ART 的相关文献进行了回顾。本病例在 2023 年举行的韩国艾滋病学会会议[艾滋病临床疑难病例探讨]上进行了讨论。