Preoperative nutritional factors as predictors of postoperative early outcomes in colorectal cancer - A prospective cohort study.

IF 2.5 4区 医学 Q3 BUSINESS
Tuba Nur Yıldız Kopuz, Hanifi Furkan Yildiz, Sadettin Er, Mehmet Fisunoglu
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引用次数: 0

Abstract

Introduction: Introduction: in colorectal cancer (CRC) surgery, preoperative nutritional factors are often overlooked or underestimated. This situation represents a significant deficiency that may negatively affect patients' postoperative recovery processes. Objective: the objective of this study was to evaluate the impact of preoperative malnutrition, sarcopenia, obesity, and dietary inflammatory potential on early postoperative outcomes in CRC. Methods: preoperative sarcopenia was identified using European Working Group on Sarcopenia in Older People (EWGSOP2) criteria based on skeletal muscle obtained from computed tomography (CT) scans, and malnutrition was identified using Global Leadership Initiative on Malnutrition (GLIM) criteria. Visceral and subcutaneous obesity were assessed using CT scans. The energy-adjusted dietary inflammatory index (E-DII) was calculated from dietary records. Results: a total of 121 patients were included in the study, and 45.5 % of them were malnourished according to GLIM, 15.7 % were sarcopenic according to EWGSOP2. Multivariate logistic regression analysis showed that sarcopenia [OR = 3.973 (1.028-15.353), p = 0.043], malnutrition [OR = 3.954 (1.479-10.575), p = 0.006], and E-DII [OR = 4.955 (1.397-17.571), p = 0.013] were independent risk factors for complications. Sarcopenia [OR = 6.894 (1.080-43.998), p = 0.041] was also risk factor for long-term hospitalization. Conclusion: a comprehensive evaluation of preoperative nutrition and related factors in CRC surgery, along with timely interventions, has the potential to significantly reduce postoperative complications and length of hospital stays.

预测结直肠癌术后早期预后的术前营养因素 - 一项前瞻性队列研究。
导言:在结直肠癌(CRC)手术中,术前营养因素往往被忽视或低估。目的:本研究旨在评估术前营养不良、肌肉疏松症、肥胖和饮食炎症潜能对 CRC 术后早期预后的影响。方法:使用欧洲老年人肌肉疏松症工作组(EWGSOP2)的标准(基于计算机断层扫描(CT)获得的骨骼肌)确定术前肌肉疏松症,使用全球营养不良领导倡议(GLIM)的标准确定营养不良。内脏和皮下肥胖通过 CT 扫描进行评估。结果:共有121名患者被纳入研究,其中45.5%的患者根据GLIM标准属于营养不良,15.7%的患者根据EWGSOP2标准属于肌肉疏松。多变量逻辑回归分析显示,肌肉疏松症[OR = 3.973 (1.028-15.353),p = 0.043]、营养不良[OR = 3.954 (1.479-10.575),p = 0.006]和 E-DII [OR = 4.955 (1.397-17.571),p = 0.013]是并发症的独立危险因素。结论:全面评估 CRC 手术的术前营养及相关因素,并及时采取干预措施,有可能显著减少术后并发症和住院时间。
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来源期刊
Nutricion hospitalaria
Nutricion hospitalaria 医学-营养学
CiteScore
1.90
自引率
8.30%
发文量
181
审稿时长
3-6 weeks
期刊介绍: The journal Nutrición Hospitalaria was born following the SENPE Bulletin (1981-1983) and the SENPE journal (1984-1985). It is the official organ of expression of the Spanish Society of Clinical Nutrition and Metabolism. Throughout its 36 years of existence has been adapting to the rhythms and demands set by the scientific community and the trends of the editorial processes, being its most recent milestone the achievement of Impact Factor (JCR) in 2009. Its content covers the fields of the sciences of nutrition, with special emphasis on nutritional support.
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