{"title":"Multiple exostoses and an osteochondroma in a Pliocene canid from Langebaanweg 'E' Quarry (South Africa).","authors":"Anusuya Chinsamy, Alberto Valenciano","doi":"10.1111/joa.14133","DOIUrl":null,"url":null,"abstract":"<p><p>Langebaanweg is a Mio-Pliocene locality located on the West Coast of South Africa. It is renowned for its rich diversity of both terrestrial and marine vertebrate fossils. Several carnivorans have been identified from this site, amongst which is the recently described jackal-like canid, Eucyon khoikhoi. One of the skeletons assigned to E. khoikhoi exhibits anatomical deformities on several bones of the skeleton. Here, we use multiple methodologies (anatomical descriptions, CT scanning and histology) to investigate the bony overgrowths or exostoses evident in the radius, and we compare these findings with those of a radius from a healthy individual of the same species from Langebaanweg. Our results show that anatomical observations are important for first level observation of the pathology, but that micro-CT scanning permits a more precise assessment of how the pathology affected the internal organization of the bone, both periosteally and endosteally. This methodology permitted us to diagnose the tumors as benign rather than cancerous. Our observations of calcified cartilage in the histological thin sections in the region of the exostosis allowed us to further diagnose the exostosis as an osteochondroma. This study has demonstrated the usefulness of applying multiple techniques to characterize and diagnose pathological bony growths in a fossil canivoran. We have also demonstrated the usefulness of histological studies in permitting a more refined diagnosis of the exostosis as an osteochondroma.</p>","PeriodicalId":14971,"journal":{"name":"Journal of Anatomy","volume":null,"pages":null},"PeriodicalIF":1.8000,"publicationDate":"2024-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Anatomy","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1111/joa.14133","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ANATOMY & MORPHOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Langebaanweg is a Mio-Pliocene locality located on the West Coast of South Africa. It is renowned for its rich diversity of both terrestrial and marine vertebrate fossils. Several carnivorans have been identified from this site, amongst which is the recently described jackal-like canid, Eucyon khoikhoi. One of the skeletons assigned to E. khoikhoi exhibits anatomical deformities on several bones of the skeleton. Here, we use multiple methodologies (anatomical descriptions, CT scanning and histology) to investigate the bony overgrowths or exostoses evident in the radius, and we compare these findings with those of a radius from a healthy individual of the same species from Langebaanweg. Our results show that anatomical observations are important for first level observation of the pathology, but that micro-CT scanning permits a more precise assessment of how the pathology affected the internal organization of the bone, both periosteally and endosteally. This methodology permitted us to diagnose the tumors as benign rather than cancerous. Our observations of calcified cartilage in the histological thin sections in the region of the exostosis allowed us to further diagnose the exostosis as an osteochondroma. This study has demonstrated the usefulness of applying multiple techniques to characterize and diagnose pathological bony growths in a fossil canivoran. We have also demonstrated the usefulness of histological studies in permitting a more refined diagnosis of the exostosis as an osteochondroma.
期刊介绍:
Journal of Anatomy is an international peer-reviewed journal sponsored by the Anatomical Society. The journal publishes original papers, invited review articles and book reviews. Its main focus is to understand anatomy through an analysis of structure, function, development and evolution. Priority will be given to studies of that clearly articulate their relevance to the anatomical community. Focal areas include: experimental studies, contributions based on molecular and cell biology and on the application of modern imaging techniques and papers with novel methods or synthetic perspective on an anatomical system.
Studies that are essentially descriptive anatomy are appropriate only if they communicate clearly a broader functional or evolutionary significance. You must clearly state the broader implications of your work in the abstract.
We particularly welcome submissions in the following areas:
Cell biology and tissue architecture
Comparative functional morphology
Developmental biology
Evolutionary developmental biology
Evolutionary morphology
Functional human anatomy
Integrative vertebrate paleontology
Methodological innovations in anatomical research
Musculoskeletal system
Neuroanatomy and neurodegeneration
Significant advances in anatomical education.