Advancing sustainable biotechnology through protein engineering.

IF 3.5 2区生物学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY

ACS Chemical Biology Pub Date : 2024-11-01 Epub Date: 2024-09-03 DOI:10.1016/j.tibs.2024.07.006

Amelia R Bergeson, Hal S Alper

引用次数: 0

Abstract

The push for industrial sustainability benefits from the use of enzymes as a replacement for traditional chemistry. Biological catalysts, especially those that have been engineered for increased activity, stability, or novel function, and are often greener than alternative chemical approaches. This Review highlights the role of engineered enzymes (and identifies directions for further engineering efforts) in the application areas of greenhouse gas sequestration, fuel production, bioremediation, and degradation of plastic wastes.

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通过蛋白质工程推进可持续生物技术。

使用酶来替代传统化学，有利于推动工业可持续发展。生物催化剂，特别是那些为提高活性、稳定性或新功能而设计的催化剂，通常比替代化学方法更环保。本综述强调了工程酶在温室气体封存、燃料生产、生物修复和塑料废物降解等应用领域的作用（并确定了进一步工程努力的方向）。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

ACS Chemical Biology 生物-生化与分子生物学

CiteScore

7.50

自引率

5.00%

发文量

353

审稿时长

3.3 months

期刊介绍： ACS Chemical Biology provides an international forum for the rapid communication of research that broadly embraces the interface between chemistry and biology. The journal also serves as a forum to facilitate the communication between biologists and chemists that will translate into new research opportunities and discoveries. Results will be published in which molecular reasoning has been used to probe questions through in vitro investigations, cell biological methods, or organismic studies. We welcome mechanistic studies on proteins, nucleic acids, sugars, lipids, and nonbiological polymers. The journal serves a large scientific community, exploring cellular function from both chemical and biological perspectives. It is understood that submitted work is based upon original results and has not been published previously.