Update on Antisocial Personality Disorder.

IF 5.5 2区 医学 Q1 PSYCHIATRY
Current Psychiatry Reports Pub Date : 2024-10-01 Epub Date: 2024-09-04 DOI:10.1007/s11920-024-01528-x
Donald W Black
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引用次数: 0

Abstract

Purpose of review: Antisocial personality disorder (ASPD) is a characterized by lifelong or recurrent behavioral problems that begin in childhood or early adolescence. This communication provides an overview on ASPD including findings from recent reviews and new research.

Recent findings: With regard to DSM-5's Section III Alternative Model of Personality Disorder criteria for ASPD, advocates point to the broader symptom coverage and harmonization with ICD-11; yet critics point to the lack of evidence for improved outcomes. A new report shows that antisocial individuals age faster than non-antisocial peers. ASPD has high heritability and newer molecular studies have found intriguing linkages to genes associated with crucial brain regions. A mentalization-based therapy model has been developed and early work shows promise. ASPD is common, widespread, and disruptive to individuals, families, and society. Chronic and lifelong, ASPD typically lessens in severity with advancing age. Assessment rests on the individual's history because there are no diagnostic tests. ASPD likely results from an interplay of genetic and environmental factors. Brain imaging studies have linked cortical dysfunction to antisocial behavior in crucial brain regions. Medication is sometimes targeted at the individual's aggression and irritability, but a more rational approach is to target co-occurring disorders. Cognitive-behavioral therapy and mentalization-based therapy models have been developed and are being studied.

反社会人格障碍的最新情况。
审查目的:反社会型人格障碍(Antisocial personality disorder,ASPD)的特征是终生或反复出现行为问题,这些问题始于童年或青春期早期。本通讯概述了反社会型人格障碍的情况,包括近期综述和新研究的发现:关于 DSM-5 第三部分人格障碍替代模式中的反社会人格障碍标准,倡导者指出其症状覆盖面更广,与 ICD-11 协调一致;但批评者指出缺乏改善结果的证据。一份新的报告显示,反社会个体比非反社会同龄人衰老得更快。反社会人格障碍具有很高的遗传性,而最新的分子研究发现,反社会人格障碍与关键脑区的相关基因有着耐人寻味的联系。一种基于心智化的治疗模式已经开发出来,早期工作显示出了良好的前景。ASPD 很常见、很普遍,对个人、家庭和社会都具有破坏性。ASPD 是一种慢性和终身性疾病,其严重程度通常会随着年龄的增长而减轻。由于没有诊断测试,评估主要依靠个人的病史。ASPD 很可能是遗传和环境因素相互作用的结果。脑成像研究表明,大脑皮质功能障碍与关键脑区的反社会行为有关。药物治疗有时针对的是患者的攻击性和易怒性,但更合理的方法是针对并发症。认知行为疗法和以心智化为基础的疗法模式已经开发出来,目前正在研究之中。
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来源期刊
CiteScore
11.30
自引率
3.00%
发文量
68
审稿时长
6-12 weeks
期刊介绍: This journal aims to review the most important, recently published research in psychiatry. By providing clear, insightful, balanced contributions by international experts, the journal intends to serve all those involved in the care of those affected by psychiatric disorders. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas, such as anxiety, medicopsychiatric disorders, and schizophrenia and other related psychotic disorders. Section Editors, in turn, select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. An international Editorial Board reviews the annual table of contents, suggests articles of special interest to their country/region, and ensures that topics are current and include emerging research. Commentaries from well-known figures in the field are also provided.
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